[HTML][HTML] Disease-associated metabolic pathways affected by heavy metals and metalloid

Z Haidar, K Fatema, SS Shoily, AA Sajib - Toxicology Reports, 2023 - Elsevier
Increased exposure to environmental heavy metals and metalloids and their associated
toxicities has become a major threat to human health. Hence, the association of these …

Biological consequences of vanadium effects on formation of reactive oxygen species and lipid peroxidation

M Aureliano, AL De Sousa-Coelho, CC Dolan… - International journal of …, 2023 - mdpi.com
Lipid peroxidation (LPO), a process that affects human health, can be induced by exposure
to vanadium salts and compounds. LPO is often exacerbated by oxidation stress, with some …

[HTML][HTML] Polyoxidovanadates' interactions with proteins: An overview

M Aureliano, NI Gumerova, G Sciortino… - Coordination Chemistry …, 2022 - Elsevier
Polyoxidovanadates (POVs, previously named polyoxovanadates) are a subgroup of
polyoxidometalates (POMs, previously named polyoxometalates) with interesting …

Vanadium in biological action: chemical, pharmacological aspects, and metabolic implications in diabetes mellitus

S Treviño, A Díaz, E Sánchez-Lara… - Biological trace element …, 2019 - Springer
Vanadium compounds have been primarily investigated as potential therapeutic agents for
the treatment of various major health issues, including cancer, atherosclerosis, and …

Molecular events associated with reactive oxygen species and cell cycle progression in mammalian cells

J Boonstra, JA Post - Gene, 2004 - Elsevier
Cell cycle progression is regulated by a wide variety of external factors, amongst them are
growth factors and extracellular matrix factors. During the last decades evidence has been …

Metal-induced oxidative stress and signal transduction

SS Leonard, GK Harris, X Shi - Free Radical Biology and Medicine, 2004 - Elsevier
Occupational and environmental exposures to metals are associated with the development
of various cancers. Although carcinogenesis caused by metals has been intensively …

Oxidative stress and metal carcinogenesis

JC Lee, YO Son, P Pratheeshkumar, X Shi - Free radical biology and …, 2012 - Elsevier
Occupational and environmental exposures to metals are closely associated with an
increased risk of various cancers. Although carcinogenesis caused by metals has been …

[PDF][PDF] Biochemical and medical importance of vanadium compounds

J Korbecki, I Baranowska-Bosiacka… - Acta Biochimica …, 2012 - frontierspartnerships.org
Vanadium belongs to the group of transition metals and is present in the air and soil
contaminants in large urban agglomerations due to combustion of fossil fuels. It forms …

Fucoxanthin induces apoptosis in human leukemia HL-60 cells through a ROS-mediated Bcl-xL pathway

KN Kim, SJ Heo, SM Kang, G Ahn, YJ Jeon - Toxicology in vitro, 2010 - Elsevier
Fucoxanthin, a natural biologically active substance isolated from Ishige okamurae,
evidences antitumor activity in human leukemia cell HL-60 cells via the induction of …

Asiatic acid, a triterpene, induces apoptosis and cell cycle arrest through activation of extracellular signal-regulated kinase and p38 mitogen-activated protein kinase …

YL Hsu, PL Kuo, LT Lin, CC Lin - The Journal of pharmacology and …, 2005 - Elsevier
This study first investigates the anticancer effect of asiatic acid in two human breast cancer
cell lines, MCF-7 and MDA-MB-231. Asiatic acid exhibited effective cell growth inhibition by …