Hyperserotonemia is one of the most studied endophenotypes in autism spectrum disorder
(ASD), but there are still no unequivocal results about its causes or biological and …

Nearly 25 years ago, Dr. Patricia Goldman-Rakic published her review paper,“The
'Psychic'Neuron of the Cerebral Cortex,” outlining the circuit-level dynamics …

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
impaired social interactions, communication deficits and repetitive behaviors. A study of …

Increasing evidence links air pollution (AP) exposure to effects on the central nervous
system structure and function. Particulate matter AP, especially the ultrafine (nanoparticle) …

Neurodevelopmental disorders (NDDs) are complex disorders which can be associated with
many comorbidities and exhibit multifactorial-dependent phenotypes. An important …

This study aims to validate the five repetition sit to stand test (5R-STS) test as a measure of
strength and functionality in adolescents and adults with intellectual disabilities (ID). The …

Abstract Chromogranin A (CgA), a∼ 49 kDa acidic secretory protein, is ubiquitously
distributed in endocrine and neuroendocrine cells and neurons. As a propeptide, CgA is …

Aims The dopamine-and cAMP-regulated phosphoprotein (DARPP-32), which is encoded
by the PPP1R1B gene, plays a converging regulatory role in the central nervous system by …

A Perturbação do Espectro do Autismo (PEA) caracteriza-se por défices na comunicação e
na interação social e por padrões repetitivos e restritos do comportamento, eventualmente …

Background: The CHD8 gene encodes chromodomain helicase DNA-binding protein 8
(CHD8), which is a transcriptional regulator involved in neuron development, myelination …