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Antimicrobial peptides: classification, design, application and research progress in multiple fields
Y Huan, Q Kong, H Mou, H Yi - Frontiers in microbiology, 2020 - frontiersin.org
Antimicrobial peptides (AMPs) are a class of small peptides that widely exist in nature and
they are an important part of the innate immune system of different organisms. AMPs have a …
they are an important part of the innate immune system of different organisms. AMPs have a …
The antimicrobial peptides and their potential clinical applications
J Lei, L Sun, S Huang, C Zhu, P Li, J He… - American journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Nowadays, the bacterial drug resistance leads to serious healthy problem worldwide due to
the long-term use and the abuse of traditional antibiotics result in drug resistance of bacteria …
the long-term use and the abuse of traditional antibiotics result in drug resistance of bacteria …
Accelerated antimicrobial discovery via deep generative models and molecular dynamics simulations
The de novo design of antimicrobial therapeutics involves the exploration of a vast chemical
repertoire to find compounds with broad-spectrum potency and low toxicity. Here, we report …
repertoire to find compounds with broad-spectrum potency and low toxicity. Here, we report …
Lessons learned from clinical trials using antimicrobial peptides (AMPs)
GS Dijksteel, MMW Ulrich, E Middelkoop… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial peptides (AMPs) or host defense peptides protect the host against various
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …
pathogens such as yeast, fungi, viruses and bacteria. AMPs also display immunomodulatory …
Antimicrobial peptides: challenging journey to the pharmaceutical, biomedical, and cosmeceutical use
A Mazurkiewicz-Pisarek, J Baran, T Ciach - International journal of …, 2023 - mdpi.com
Antimicrobial peptides (AMPs), or host defence peptides, are short proteins in various life
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …
forms. Here we discuss AMPs, which may become a promising substitute or adjuvant in …
[HTML][HTML] An overview of biofilm formation–combating strategies and mechanisms of action of antibiofilm agents
Biofilm formation on surfaces via microbial colonization causes infections and has become a
major health issue globally. The biofilm lifestyle provides resistance to environmental …
major health issue globally. The biofilm lifestyle provides resistance to environmental …
The demand for new antibiotics: antimicrobial peptides, nanoparticles, and combinatorial therapies as future strategies in antibacterial agent design
A León-Buitimea, CR Garza-Cárdenas… - Frontiers in …, 2020 - frontiersin.org
The inappropriate use of antibiotics and an inadequate control of infections have led to the
emergence of resistant strains which represent a major threat to public health and the global …
emergence of resistant strains which represent a major threat to public health and the global …
Antimicrobial peptides under clinical investigation
HB Koo, J Seo - Peptide Science, 2019 - Wiley Online Library
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …
development leads to antimicrobial resistance (AMR). Because infections with multi‐drug …
Antimicrobial peptides: new hope in the war against multidrug resistance
The discovery of antibiotics marked a golden age in the revolution of human medicine.
However, decades later, bacterial infections remain a global healthcare threat, and a return …
However, decades later, bacterial infections remain a global healthcare threat, and a return …
A review on antimicrobial peptides databases and the computational tools
S Ramazi, N Mohammadi, A Allahverdi, E Khalili… - Database, 2022 - academic.oup.com
Abstract Antimicrobial Peptides (AMPs) have been considered as potential alternatives for
infection therapeutics since antibiotic resistance has been raised as a global problem. The …
infection therapeutics since antibiotic resistance has been raised as a global problem. The …