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Biological and biomedical implications of the co-evolution of pathogens and their hosts
Co-evolution between host and pathogen is, in principle, a powerful determinant of the
biology and genetics of infection and disease. Yet co-evolution has proven difficult to …
biology and genetics of infection and disease. Yet co-evolution has proven difficult to …
T cell dynamics in HIV-1 infection
▪ Abstract In the absence of antiretroviral treatment, HIV-1 establishes a chronic, progressive
infection of the human immune system that invariably, over the course of years, leads to its …
infection of the human immune system that invariably, over the course of years, leads to its …
HIV preferentially infects HIV-specific CD4+ T cells
HIV infection is associated with the progressive loss of CD4+ T cells through their
destruction or decreased production,. A central, yet unresolved issue of HIV disease is the …
destruction or decreased production,. A central, yet unresolved issue of HIV disease is the …
Long-term antiretroviral treatment initiated at primary HIV-1 infection affects the size, composition, and decay kinetics of the reservoir of HIV-1-infected CD4 T cells
Initiation of antiretroviral therapy during the earliest stages of HIV-1 infection may limit the
seeding of a long-lasting viral reservoir, but long-term effects of early antiretroviral treatment …
seeding of a long-lasting viral reservoir, but long-term effects of early antiretroviral treatment …
[ספר][B] HIV and the pathogenesis of AIDS.
JA Levy - 1994 - cabidigitallibrary.org
This book grew out of a scientific review, originally published in Microbiological Reviews. It
has been updated and expanded-now citing more than 2100 references (100 pages of the …
has been updated and expanded-now citing more than 2100 references (100 pages of the …
Analysis of Total Human Immunodeficiency Virus (HIV)-Specific CD4+ and CD8+ T-Cell Responses: Relationship to Viral Load in Untreated HIV Infection
Human immunodeficiency virus (HIV)-specific T-cell responses are thought to play a key role
in viral load decline during primary infection and in determining the subsequent viral load …
in viral load decline during primary infection and in determining the subsequent viral load …
Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome …
Cellular immune responses play a critical role in the control of human immunodeficiency
virus type 1 (HIV-1); however, the breadth of these responses at the single-epitope level has …
virus type 1 (HIV-1); however, the breadth of these responses at the single-epitope level has …
The T-cell response to HIV
HIV is a disease in which the original clinical observations of severe opportunistic infections
gave the first clues regarding the underlying pathology, namely that HIV is essentially an …
gave the first clues regarding the underlying pathology, namely that HIV is essentially an …
Sequential deregulation of NK cell subset distribution and function starting in acute HIV-1 infection
Natural killer (NK) cells are critical in the first-line defense against viral infections. Chronic
HIV-1 infection leads to a perturbation in the NK cell compartment, yet the kinetics of this …
HIV-1 infection leads to a perturbation in the NK cell compartment, yet the kinetics of this …
Evolution and transmission of stable CTL escape mutations in HIV infection
Increasing evidence indicates that potent anti-HIV-1 activity is mediated by cytotoxic T
lymphocytes (CTLs),,; however, the effects of this immune pressure on viral transmission and …
lymphocytes (CTLs),,; however, the effects of this immune pressure on viral transmission and …