Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

Fluorescence lifetime measurements and biological imaging

MY Berezin, S Achilefu - Chemical reviews, 2010 - ACS Publications
When a molecule absorbs a photon of appropriate energy, a chain of photophysical events
ensues, such as internal conversion or vibrational relaxation (loss of energy in the absence …

Nanoscale covalent organic frameworks for enhanced photocatalytic hydrogen production

W Zhao, L Luo, M Cong, X Liu, Z Zhang, M Bahri… - Nature …, 2024 - nature.com
Nanosizing confers unique functions in materials such as graphene and quantum dots.
Here, we present two nanoscale-covalent organic frameworks (nano-COFs) that exhibit …

MicroRNA detection specificity: recent advances and future perspective

T Ouyang, Z Liu, Z Han, Q Ge - Analytical chemistry, 2019 - ACS Publications
MicroRNAs (miRNAs) are a series of promising molecules that could regulate gene
expression, while its expression level and type are strictly related to the early diagnosis …

Excitation wavelength dependent fluorescence of an ESIPT triazole derivative for amine sensing and anti‐counterfeiting applications

Y Zhang, H Yang, H Ma, G Bian, Q Zang… - Angewandte Chemie …, 2019 - Wiley Online Library
Abstract Excitation wavelength dependent (Ex‐De) emission materials have potential
applications in anti‐counterfeiting labels and bioimaging. Nevertheless, few purely organic …

Rationally designed molecular beacons for bioanalytical and biomedical applications

J Zheng, R Yang, M Shi, C Wu, X Fang, Y Li… - Chemical Society …, 2015 - pubs.rsc.org
Nucleic acids hold promise as biomolecules for future applications in biomedicine and
biotechnology. Their well-defined structures and compositions afford unique chemical …

Pyrene‐excimer probes based on the hybridization chain reaction for the detection of nucleic acids in complex biological fluids

J Huang, Y Wu, Y Chen, Z Zhu, X Yang… - Angewandte Chemie …, 2011 - Wiley Online Library
The sensitive and selective detection of nucleic acids is important in biological studies,
clinical diagnostics, and biodefense applications. Since the DNA sequences of interest may …

Molecular engineering of DNA: molecular beacons

K Wang, Z Tang, CJ Yang, Y Kim… - Angewandte Chemie …, 2009 - Wiley Online Library
Molecular beacons (MBs) are specifically designed DNA hairpin structures that are widely
used as fluorescent probes. Applications of MBs range from genetic screening, biosensor …

Luminescent covalent organic frameworks for biosensing and bioimaging applications

J Ma, T Shu, Y Sun, X Zhou, C Ren, L Su, X Zhang - Small, 2022 - Wiley Online Library
Luminescent covalent organic frameworks (LCOFs) have attracted significant attention due
to their tunability of structures and photophysical properties at molecular level. LCOFs are …

Pyrene: a probe to study protein conformation and conformational changes

G Bains, AB Patel, V Narayanaswami - Molecules, 2011 - mdpi.com
The review focuses on the unique spectral features of pyrene that can be utilized to
investigate protein structure and conformation. Pyrene is a fluorescent probe that can be …