Chalcone derivatives and their antibacterial activities: Current development
M Xu, P Wu, F Shen, J Ji, KP Rakesh - Bioorganic Chemistry, 2019 - Elsevier
The increase in antibiotic resistance due to various factors has encouraged the look for
novel compounds which are active against multidrug-resistant pathogens. In this framework …
novel compounds which are active against multidrug-resistant pathogens. In this framework …
Synthetic chemistry of pyrimidines and fused pyrimidines: A review
S Mohana Roopan, R Sompalle - Synthetic Communications, 2016 - Taylor & Francis
This review is an attempt to compile the literature of various synthetic procedures of
pyrimidine analogs. Pyrimidine and its fused pyrimidine derivatives are a class of …
pyrimidine analogs. Pyrimidine and its fused pyrimidine derivatives are a class of …
Activation of Nrf2 signaling pathway by natural and synthetic chalcones: A therapeutic road map for oxidative stress
Introduction: Nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway plays a key
role in diverse gene expressions responsible for protection against oxidative stress and …
role in diverse gene expressions responsible for protection against oxidative stress and …
Design, synthesis, characterization and anticancer activity evaluation of deoxycholic acid-chalcone conjugates
A series of deoxycholic acid-chalcone amides were synthesised and tested against the
human lung cancer cell line, A549 and the cervical cancer cell line, SiHa. Among the …
human lung cancer cell line, A549 and the cervical cancer cell line, SiHa. Among the …
Antimicrobial, anti-inflammatory and antioxidant activities of polyoxygenated chalcones
YA Vásquez-Martínez, ME Osorio… - Journal of the Brazilian …, 2019 - SciELO Brasil
It was synthesized nine polyoxygenated chalcones with a potential and safe use as
antioxidant, antimicrobial and anti-inflammatory therapies. Chalcones obtained by Claisen …
antioxidant, antimicrobial and anti-inflammatory therapies. Chalcones obtained by Claisen …
Synthesis, antifungal evaluation, and molecular docking studies of steroidal thiazolopyrimidines
A series of steroidal thiazolopyrimidine derivatives were developed and evaluated for their
antifungal properties against Candida species using steroid as the basic skeleton and a …
antifungal properties against Candida species using steroid as the basic skeleton and a …
A novel [1, 2, 4] triazolo [1, 5-a] pyrimidine-based phenyl-linked steroid dimer: Synthesis and its cytotoxic activity
Abstract A novel [1, 2, 4] triazolo [1, 5-a] pyrimidine-based phenyl-linked steroid dimer was
designed, synthesized and evaluated for its cytotoxic activity against five human cancer cell …
designed, synthesized and evaluated for its cytotoxic activity against five human cancer cell …
Unsubstituted oximes as potential therapeutic agents
Oximes, which are highly bioactive molecules, have versatile uses in the medical sector and
have been indicated to possess biological activity. Certain oximes exist in nature in plants …
have been indicated to possess biological activity. Certain oximes exist in nature in plants …
Synthesis and biological evaluation of new steroidal pyridines as potential anti-prostate cancer agents
YK Shi, B Wang, XL Shi, YD Zhao, B Yu… - European Journal of …, 2018 - Elsevier
A series of new steroidal pyridines have been synthesized through the based-promoted
three-component reaction and preliminarily evaluated for their antiproliferative activity …
three-component reaction and preliminarily evaluated for their antiproliferative activity …
Synthesis, characterization and antitumor activities of some steroidal derivatives with side chain of 17-hydrazone aromatic heterocycle
J Cui, L Liu, D Zhao, C Gan, X Huang, Q **ao, B Qi… - Steroids, 2015 - Elsevier
Here a series of dehydroepiandrosterone-17-hydrazone and estrone-17-hydrazone
derivatives possessing various aromatic heterocycle structures in 17-side chain of their …
derivatives possessing various aromatic heterocycle structures in 17-side chain of their …