Chalcone derivatives and their antibacterial activities: Current development

M Xu, P Wu, F Shen, J Ji, KP Rakesh - Bioorganic Chemistry, 2019 - Elsevier
The increase in antibiotic resistance due to various factors has encouraged the look for
novel compounds which are active against multidrug-resistant pathogens. In this framework …

Synthetic chemistry of pyrimidines and fused pyrimidines: A review

S Mohana Roopan, R Sompalle - Synthetic Communications, 2016 - Taylor & Francis
This review is an attempt to compile the literature of various synthetic procedures of
pyrimidine analogs. Pyrimidine and its fused pyrimidine derivatives are a class of …

Activation of Nrf2 signaling pathway by natural and synthetic chalcones: A therapeutic road map for oxidative stress

MC Egbujor, S Saha, B Buttari, E Profumo… - Expert review of clinical …, 2021 - Taylor & Francis
Introduction: Nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway plays a key
role in diverse gene expressions responsible for protection against oxidative stress and …

Design, synthesis, characterization and anticancer activity evaluation of deoxycholic acid-chalcone conjugates

S Patel, N Challagundla, RA Rajput, S Mishra - Bioorganic Chemistry, 2022 - Elsevier
A series of deoxycholic acid-chalcone amides were synthesised and tested against the
human lung cancer cell line, A549 and the cervical cancer cell line, SiHa. Among the …

Antimicrobial, anti-inflammatory and antioxidant activities of polyoxygenated chalcones

YA Vásquez-Martínez, ME Osorio… - Journal of the Brazilian …, 2019 - SciELO Brasil
It was synthesized nine polyoxygenated chalcones with a potential and safe use as
antioxidant, antimicrobial and anti-inflammatory therapies. Chalcones obtained by Claisen …

Synthesis, antifungal evaluation, and molecular docking studies of steroidal thiazolopyrimidines

A Iqbal, A Khan, S Ahmedi, N Manzoor, T Siddiqui - Steroids, 2023 - Elsevier
A series of steroidal thiazolopyrimidine derivatives were developed and evaluated for their
antifungal properties against Candida species using steroid as the basic skeleton and a …

A novel [1, 2, 4] triazolo [1, 5-a] pyrimidine-based phenyl-linked steroid dimer: Synthesis and its cytotoxic activity

B Yu, XJ Shi, YF Zheng, Y Fang, E Zhang… - European Journal of …, 2013 - Elsevier
Abstract A novel [1, 2, 4] triazolo [1, 5-a] pyrimidine-based phenyl-linked steroid dimer was
designed, synthesized and evaluated for its cytotoxic activity against five human cancer cell …

Unsubstituted oximes as potential therapeutic agents

AK Surowiak, S Lochyński, DJ Strub - Symmetry, 2020 - mdpi.com
Oximes, which are highly bioactive molecules, have versatile uses in the medical sector and
have been indicated to possess biological activity. Certain oximes exist in nature in plants …

Synthesis and biological evaluation of new steroidal pyridines as potential anti-prostate cancer agents

YK Shi, B Wang, XL Shi, YD Zhao, B Yu… - European Journal of …, 2018 - Elsevier
A series of new steroidal pyridines have been synthesized through the based-promoted
three-component reaction and preliminarily evaluated for their antiproliferative activity …

Synthesis, characterization and antitumor activities of some steroidal derivatives with side chain of 17-hydrazone aromatic heterocycle

J Cui, L Liu, D Zhao, C Gan, X Huang, Q **ao, B Qi… - Steroids, 2015 - Elsevier
Here a series of dehydroepiandrosterone-17-hydrazone and estrone-17-hydrazone
derivatives possessing various aromatic heterocycle structures in 17-side chain of their …