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ROS: Basic concepts, sources, cellular signaling, and its implications in aging pathways
AJPO de Almeida, JCPL de Oliveira… - Oxidative medicine …, 2022 - Wiley Online Library
Reactive oxygen species (ROS) are bioproducts of cellular metabolism. There is a range of
molecules with oxidizing properties known as ROS. Despite those molecules being implied …
molecules with oxidizing properties known as ROS. Despite those molecules being implied …
Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation
The core pathology of coronavirus disease 2019 (COVID-19) is infection of airway cells by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that results in excessive …
Hypertension-induced cognitive impairment: from pathophysiology to public health
Hypertension affects two-thirds of people aged> 60 years and significantly increases the risk
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …
of both vascular cognitive impairment and Alzheimer's disease. Hypertension compromises …
The multifaceted benefits of walking for healthy aging: from Blue Zones to molecular mechanisms
Physical activity, including walking, has numerous health benefits in older adults, supported
by a plethora of observational and interventional studies. Walking decreases the risk or …
by a plethora of observational and interventional studies. Walking decreases the risk or …
[HTML][HTML] COVID-19-associated cardiovascular morbidity in older adults: a position paper from the Italian Society of Cardiovascular Researches
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells following
binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 …
binding with the cell surface ACE2 receptors, thereby leading to coronavirus disease 2019 …
Exposome and unhealthy aging: environmental drivers from air pollution to occupational exposures
The aging population worldwide is facing a significant increase in age-related non-
communicable diseases, including cardiovascular and brain pathologies. This …
communicable diseases, including cardiovascular and brain pathologies. This …
New dawn for atherosclerosis: vascular endothelial cell senescence and death
LL Bu, HH Yuan, LL **e, MH Guo, DF Liao… - International journal of …, 2023 - mdpi.com
Endothelial cells (ECs) form the inner linings of blood vessels, and are directly exposed to
endogenous hazard signals and metabolites in the circulatory system. The senescence and …
endogenous hazard signals and metabolites in the circulatory system. The senescence and …
Endothelial Dysfunction, Inflammation, and Oxidative Stress in COVID‐19—Mechanisms and Therapeutic Targets
The outbreak of the COVID‐19 pandemic represents an ongoing healthcare emergency
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …
responsible for more than 3.4 million deaths worldwide. COVID‐19 is the disease caused by …
[HTML][HTML] Polychemotherapy with curcumin and doxorubicin via biological nanoplatforms: enhancing antitumor activity
Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …
[PDF][PDF] Geroscience and pathology: a new frontier in understanding age-related diseases
M Fekete, D Major, A Feher… - Pathology and …, 2024 - por-journal.com
Geroscience, an emerging discipline at the intersection of aging and disease, seeks to
understand the relationship between the aging process and pathogenesis of age-related …
understand the relationship between the aging process and pathogenesis of age-related …