Brown and beige fat: development, function and therapeutic potential
M Harms, P Seale - Nature medicine, 2013 - nature.com
Adipose tissue, best known for its role in fat storage, can also suppress weight gain and
metabolic disease through the action of specialized, heat-producing adipocytes. Brown …
metabolic disease through the action of specialized, heat-producing adipocytes. Brown …
Brown adipose tissue energy metabolism in humans
The demonstration of metabolically active brown adipose tissue (BAT) in humans primarily
using positron emission tomography coupled to computed tomography (PET/CT) with the …
using positron emission tomography coupled to computed tomography (PET/CT) with the …
Recruited brown adipose tissue as an antiobesity agent in humans
T Yoneshiro, S Aita, M Matsushita… - The Journal of …, 2013 - Am Soc Clin Investig
Brown adipose tissue (BAT) burns fat to produce heat when the body is exposed to cold and
plays a role in energy metabolism. Using fluorodeoxyglucose-positron emission tomography …
plays a role in energy metabolism. Using fluorodeoxyglucose-positron emission tomography …
White, brown, beige/brite: different adipose cells for different functions?
M Giralt, F Villarroya - Endocrinology, 2013 - academic.oup.com
Brown adipose tissue (BAT) is a major site of nonshivering thermogenesis in mammals.
Rodent studies indicated that BAT thermogenic activity may protect against obesity. Recent …
Rodent studies indicated that BAT thermogenic activity may protect against obesity. Recent …
The different shades of fat
V Peirce, S Carobbio, A Vidal-Puig - Nature, 2014 - nature.com
Our understanding of adipose tissue biology has progressed rapidly since the turn of the
century. White adipose tissue has emerged as a key determinant of healthy metabolism and …
century. White adipose tissue has emerged as a key determinant of healthy metabolism and …
Temperature-acclimated brown adipose tissue modulates insulin sensitivity in humans
P Lee, S Smith, J Linderman, AB Courville… - Diabetes, 2014 - Am Diabetes Assoc
In rodents, brown adipose tissue (BAT) regulates cold-and diet-induced thermogenesis (CIT;
DIT). Whether BAT recruitment is reversible and how it impacts on energy metabolism have …
DIT). Whether BAT recruitment is reversible and how it impacts on energy metabolism have …
Single-nucleus transcriptomics identifies separate classes of UCP1 and futile cycle adipocytes
Adipose tissue can recruit catabolic adipocytes that utilize chemical energy to dissipate heat.
This process occurs either by uncoupled respiration through uncoupling protein 1 (UCP1) or …
This process occurs either by uncoupled respiration through uncoupling protein 1 (UCP1) or …
Lactobacillus reuteri J1 prevents obesity by altering the gut microbiota and regulating bile acid metabolism in obese mice
C Zhang, R Fang, X Lu, Y Zhang, M Yang, Y Su… - Food & Function, 2022 - pubs.rsc.org
Obesity is closely related to metabolic syndromes such as hyperlipidemia and diabetes and
has become a global public health problem. Probiotics are now used as a treatment for …
has become a global public health problem. Probiotics are now used as a treatment for …
Anatomical locations of human brown adipose tissue: functional relevance and implications in obesity and type 2 diabetes
H Sacks, ME Symonds - Diabetes, 2013 - Am Diabetes Assoc
We will review information about and present hypotheses as to the anatomy of brown
adipose tissue (BAT). Why is it located where it is in humans? Its anatomical distribution is …
adipose tissue (BAT). Why is it located where it is in humans? Its anatomical distribution is …
Human brown adipose tissue: what we have learned so far
MJ Betz, S Enerbäck - Diabetes, 2015 - Am Diabetes Assoc
Brown adipose tissue (BAT) is a unique tissue that is able to convert chemical energy
directly into heat when activated by the sympathetic nervous system. While initially believed …
directly into heat when activated by the sympathetic nervous system. While initially believed …