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Epigenetics and plant hormone dynamics: a functional and methodological perspective
J Rudolf, L Tomovicova, K Panzarova… - Journal of …, 2024 - academic.oup.com
Plant hormones, pivotal regulators of plant growth, development, and response to
environmental cues, have recently emerged as central modulators of epigenetic processes …
environmental cues, have recently emerged as central modulators of epigenetic processes …
Translational fidelity during bacterial stresses and host interactions
Translational fidelity refers to accuracy during protein synthesis and is maintained in all
three domains of life. Translational errors occur at base levels during normal conditions and …
three domains of life. Translational errors occur at base levels during normal conditions and …
tRNA epitranscriptome determines pathogenicity of the opportunistic pathogen Pseudomonas aeruginosa
J Krueger, M Preusse, N Oswaldo Gomez… - Proceedings of the …, 2024 - pnas.org
The success of bacterial pathogens depends on the coordinated expression of virulence
determinants. Regulatory circuits that drive pathogenesis are complex, multilayered, and …
determinants. Regulatory circuits that drive pathogenesis are complex, multilayered, and …
tModBase: deciphering the landscape of tRNA modifications and their dynamic changes from epitranscriptome data
Abstract tRNA molecules contain dense, abundant modifications that affect tRNA structure,
stability, mRNA decoding and tsRNA formation. tRNA modifications and related enzymes …
stability, mRNA decoding and tsRNA formation. tRNA modifications and related enzymes …
tRNA hypomodification facilitates 5-fluorocytosine resistance via cross-pathway control system activation in Aspergillus fumigatus<?mode longmeta?>
A Bruch, V Lazarova, M Berg, T Krüger… - Nucleic Acids …, 2025 - academic.oup.com
Increasing antifungal drug resistance is a major concern associated with human fungal
pathogens like Aspergillus fumigatus. Genetic mutation and epimutation mechanisms clearly …
pathogens like Aspergillus fumigatus. Genetic mutation and epimutation mechanisms clearly …
A highly conserved tRNA modification contributes to C. albicans filamentation and virulence
ABSTRACT tRNA modifications play important roles in maintaining translation accuracy in
all domains of life. Disruptions in the tRNA modification machinery, especially of the …
all domains of life. Disruptions in the tRNA modification machinery, especially of the …
Queuosine salvage in Bartonella henselae Houston 1: a unique evolutionary path
Queuosine (Q) stands out as the sole tRNA modification that can be synthesized via salvage
pathways. Comparative genomic analyses identified specific bacteria that showed a …
pathways. Comparative genomic analyses identified specific bacteria that showed a …
Past, Present, and Future of RNA Modifications in Infectious Disease Research
In early 2024, the National Academies of Sciences, Engineering, and Medicine (NASEM)
released a roadmap for the future of research into map** ribonucleic acid (RNA) …
released a roadmap for the future of research into map** ribonucleic acid (RNA) …
Aminoglycoside tolerance in Vibrio cholerae engages translational reprogramming associated with queuosine tRNA modification
Tgt is the enzyme modifying the guanine (G) in tRNAs with GUN anticodon to queuosine (Q).
tgt is required for optimal growth of Vibrio cholerae in the presence of sub-lethal …
tgt is required for optimal growth of Vibrio cholerae in the presence of sub-lethal …
Distinct impacts of each anti-anti-sigma factor ortholog of the chlamydial Rsb partner switching mechanism on development in Chlamydia trachomatis
Partner switching mechanisms (PSMs) are signal transduction systems comprised of a
sensor phosphatase (RsbU), an anti-sigma factor (RsbW, kinase), an anti-anti-sigma factor …
sensor phosphatase (RsbU), an anti-sigma factor (RsbW, kinase), an anti-anti-sigma factor …