Toll-like receptors in the pathogenesis of neuroinflammation
V Kumar - Journal of Neuroimmunology, 2019 - Elsevier
Toll-like receptors (TLRs) are discovered as crucial pattern recognition receptors (PRRs)
involved in the recognition of pathogen-associated molecular patterns (PAMPs). Later …
involved in the recognition of pathogen-associated molecular patterns (PAMPs). Later …
Extracellular vesicles derived from melatonin‐preconditioned mesenchymal stem cells containing USP29 repair traumatic spinal cord injury by stabilizing NRF2
W Liu, P Tang, J Wang, W Ye, X Ge… - Journal of Pineal …, 2021 - Wiley Online Library
Spinal cord injury (SCI) is a devastating trauma that leads to irreversible motor and sensory
dysfunction and is, so far, without effective treatment. Recently, however, nano‐sized …
dysfunction and is, so far, without effective treatment. Recently, however, nano‐sized …
Biology of Pellino1: a potential therapeutic target for inflammation in diseases and cancers
L Yan, Y Cui, J Feng - Frontiers in Immunology, 2023 - frontiersin.org
Pellino1 (Peli1) is a highly conserved E3 Ub ligase that exerts its biological functions by
mediating target protein ubiquitination. Extensive evidence has demonstrated the crucial …
mediating target protein ubiquitination. Extensive evidence has demonstrated the crucial …
Silencing of A20 aggravates neuronal death and inflammation after traumatic brain injury: a potential trigger of necroptosis
Z Bao, L Fan, L Zhao, X Xu, Y Liu, H Chao… - Frontiers in Molecular …, 2019 - frontiersin.org
Programmed cell death is an important biological process that plays an indispensable role
in traumatic brain injury (TBI). Inhibition of necroptosis, a type of programmed cell death, is …
in traumatic brain injury (TBI). Inhibition of necroptosis, a type of programmed cell death, is …
Exosomal USP13 derived from microvascular endothelial cells regulates immune microenvironment and improves functional recovery after spinal cord injury by …
X Ge, Z Zhou, S Yang, W Ye, Z Wang, J Wang, C **ao… - Cell & Bioscience, 2023 - Springer
Spinal cord injury (SCI) can result in irreversible sensory and motor disability with no
effective treatment currently. After SCI, infiltrated macrophages accumulate in epicenter …
effective treatment currently. After SCI, infiltrated macrophages accumulate in epicenter …
TRAF6-p38/JNK-ATF2 axis promotes microglial inflammatory activation
M Li, D Zhang, X Ge, X Zhu, Y Zhou, Y Zhang… - Experimental Cell …, 2019 - Elsevier
Abstract Activating transcription factor 2 (ATF2), a member of the alkaline-leucine zipper
family, is widely expressed in various tissues, and reportedly involved in inflammatory …
family, is widely expressed in various tissues, and reportedly involved in inflammatory …
Senolytics cocktail dasatinib and quercetin alleviate human umbilical vein endothelial cell senescence via the TRAF6-MAPK-NF-κB axis in a YTHDF2-dependent …
T Fan, Y Du, M Zhang, AR Zhu, J Zhang - Gerontology, 2022 - karger.com
Introduction: Senescent cells play a key role in the initiation and development of various age-
related diseases. Human umbilical vein endothelial cells (HUVECs) senescence is closely …
related diseases. Human umbilical vein endothelial cells (HUVECs) senescence is closely …
Toll-like receptors in inflammatory bowel disease: A review of the role of phytochemicals
N Esmaealzadeh, M Ram, A Abdolghaffari… - Phytomedicine, 2024 - Elsevier
Background Inflammatory bowel disease (IBD) is a chronic inflammation within the
gastrointestinal tract with a remarkable impact on patients' quality of life. Toll-like receptors …
gastrointestinal tract with a remarkable impact on patients' quality of life. Toll-like receptors …
Conditional knockout of ASK1 in microglia/macrophages attenuates epileptic seizures and long-term neurobehavioural comorbidities by modulating the inflammatory …
Y Zhang, Z Wang, R Wang, L **a, Y Cai, F Tong… - Journal of …, 2022 - Springer
Background Apoptosis signal-regulating kinase 1 (ASK1) not only causes neuronal
programmed cell death via the mitochondrial pathway but also is an essential component of …
programmed cell death via the mitochondrial pathway but also is an essential component of …
Role of pattern recognition receptors and the microbiota in neurological disorders
In recent years, the gut microbiota has been increasingly implicated in the development of
many extraintestinal disorders, including neurodevelopmental and neurodegenerative …
many extraintestinal disorders, including neurodevelopmental and neurodegenerative …