Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

Recent advances in the medical use of silver complex

X Liang, S Luan, Z Yin, M He, C He, L Yin, Y Zou… - European Journal of …, 2018 - Elsevier
Silver has been used for numerous medical conditions for centuries, however, most of the
current clinical silver agents all have their own disadvantages limiting the clinical …

Recent developments in the medicinal applications of silver-NHC complexes and imidazolium salts

NA Johnson, MR Southerland, WJ Youngs - Molecules, 2017 - mdpi.com
Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …

2-Hydroxyethyl substituted NHC precursors: Synthesis, characterization, crystal structure and carbonic anhydrase, α-glycosidase, butyrylcholinesterase, and …

F Erdemir, DB Celepci, A Aktaş, P Taslimi, Y Gök… - Journal of molecular …, 2018 - Elsevier
This study contains novel a serie synthesis of N-heterocyclic carbene (NHC) precursors that
2-hydroxyethyl substituted. The NHC precursors have been prepared from 1-(2 …

Coinage Metal N‐Heterocyclic Carbene Complexes: Recent Synthetic Strategies and Medicinal Applications

S Nayak, SL Gaonkar - ChemMedChem, 2021 - Wiley Online Library
New weapons are constantly needed in the fight against cancer. The discovery of cisplatin
as an anticancer drug prompted the search for new metal complexes. The successful history …

Synthesis and catalytic applications of palladium N-heterocyclic carbene complexes as efficient pre-catalysts for Suzuki–Miyaura and Sonogashira coupling reactions

L Boubakri, S Yasar, V Dorcet, T Roisnel… - New Journal of …, 2017 - pubs.rsc.org
A new palladium complex series with N-heterocyclic carbene (NHC), pyridine and
phosphine ligands, PdCl2 (L) NHC (2a–c)(L= NHC), PdCl2 (L1) NHC (3a–c)(L1= pyridine) …

Human colon cancer targeted pro-apoptotic, anti-metastatic and cytostatic effects of binuclear Silver (I)–N-Heterocyclic carbene (NHC) complexes

M Asif, MA Iqbal, MA Hussein, CE Oon… - European journal of …, 2016 - Elsevier
The current mechanistic study was conducted to explore the effects of increased lipophilicity
of binuclear silver (I)–NHC complexes on cytotoxicity. Two new silver (I)–N-Heterocyclic …

[HTML][HTML] Synthesis, structural characterization of silver (I)-NHC complexes and their antimicrobial, antioxidant and antitumor activities

I Slimani, L Mansour, N Abutaha, AH Harrath… - Journal of King Saud …, 2020 - Elsevier
To prepare a novel series of silver (I) complexes, the interaction of benzimidazolium salts
having their two nitrogen atoms substituted by bulky groups with Ag 2 O in DMF has been …

Novel Silver-NHC complexes: Synthesis and anticancer properties

S Şahin-Bölükbaşı, N Şahin - Journal of Organometallic Chemistry, 2019 - Elsevier
The aim of this study was to present the synthesis, characterization and anticancer activities
of two novel benzimidazole-based NHC salts (1a-b) and their silver (I) complexes (2a-b) with …

Sterically modulated silver (I) complexes of coumarin substituted benzimidazol–2–ylidenes: Synthesis, crystal structures and evaluation of their antimicrobial and …

G Achar, CR Shahini, SA Patil, JG Małecki… - Journal of Inorganic …, 2018 - Elsevier
In this contribution, a series of sterically–encumbered coumarin substituted benzimidazole–
based N–heterocyclic carbene (NHC) precursors (1− 12) and their silver (I)–NHC complexes …