Recent advances in the synthesis of nitrogen-containing heterocyclic compounds via multicomponent reaction and their emerging biological applications: a review

Mallappa, M Chahar, N Choudhary, KK Yadav… - Journal of the Iranian …, 2024 - Springer
Nitrogen-containing heterocyclic compounds (NCHCs) have an important role in the field of
medicinal chemistry due to their extensive biological activities and their prevalence in …

Mini-Reviewing the Synthesis of Dihydropyrimidine Derivatives

D Katariya, A Vyas, R Khunt - Reviews and Advances in Chemistry, 2025 - Springer
The synthesis of dihydropyrimidine derivatives, vital for their broad biological activities, has
seen significant advancements through the development of efficient and sustainable …

Metal-organic framework catalysed multicomponent reactions towards the synthesis of Pyrans

SI Bhat, C Bhat - Heliyon, 2025 - cell.com
Abstract Metal-Organic Frameworks (MOFs) gaining increasing interest in heterogeneous
catalysis owing to their advantageous properties such as superior porosity, high surface …

Environmentally conscious synthesis of novel pyrano [2, 3-d] pyrimidines via ternary deep eutectic solvents

SL Kumar, S Tabassum, S Govindaraju - Journal of Molecular Liquids, 2025 - Elsevier
Abstract Pyrano [2, 3-d] pyrimidine and its analogues have gained considerable courtesy
because of their diverse biological functions and wide-ranging applications, from …

Tandem Synthesis and Computational Insights into Triazole and Pyrazole-Based Pyridine Derivatives Targeting EGFR-TK in Cancer Therapy

S Bondock, N Alabbad, RH Abd El-Aleam… - Polycyclic Aromatic …, 2024 - Taylor & Francis
Cancer remains one of the leading causes of death worldwide, despite significant advances
in treatment. Targeting tyrosine kinases, such as the epidermal growth factor receptor …

Synthesis of Heterocyclic Compounds with Pyrimidine-4-carbaldehydes as Key Intermediates

A Mavroskoufis, S Deckert, C Fopp, H Hertwig… - …, 2025 - thieme-connect.com
With the motivation to expand the compound library of specifically substituted pyrimidine
derivatives, we prepared several pyrimidine-4-carbaldehydes. In most cases, the …

Exploring the Efficiency of Oxone®/Ki as a Catalyst in the Synthesis of Spirocyclopropylbarbiturate Derivatives Via Michael-Initiated Reaction Cyclization (Mirc)

E Kolvari, A Rezaeifard, N Koukabi - Ki as a Catalyst in the Synthesis of … - papers.ssrn.com
This study investigates the innovative use of Oxone®/KI as a catalyst in synthesizing
spirocyclopropylbarbiturate (SCPB) derivatives via the Michael-initiated reaction cyclization …