Ketone bodies: from enemy to friend and guardian angel
H Kolb, K Kempf, M Röhling, M Lenzen-Schulte… - BMC medicine, 2021 - Springer
During starvation, fasting, or a diet containing little digestible carbohydrates, the circulating
insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the …
insulin levels are decreased. This promotes lipolysis, and the breakdown of fat becomes the …
Tea tree oil, a vibrant source of neuroprotection via neuroinflammation inhibition: a critical insight into repurposing Melaleuca alternifolia by unfolding its …
Over the past few decades, complementary and alternative treatments have become
increasingly popular worldwide. The purported therapeutic characteristics of natural …
increasingly popular worldwide. The purported therapeutic characteristics of natural …
[HTML][HTML] High concentrations of fatty acids and β-hydroxybutyrate impair the growth hormone-mediated hepatic JAK2-STAT5 pathway in clinically ketotic cows
The hepatic growth hormone (GH)–insulin-like growth factor (IGF)-I axis is essential for
regulating intrahepatic lipid metabolism. Ketotic cows are characterized by high blood …
regulating intrahepatic lipid metabolism. Ketotic cows are characterized by high blood …
[HTML][HTML] Transcriptomic and metabolomic insights into the roles of exogenous β-hydroxybutyrate acid for the development of rumen epithelium in young goats
Abstract Beta-hydroxybutyric acid (BHBA), as one of the main metabolic ketones in the
rumen epithelium, plays critical roles in cellular growth and metabolism. The ketogenic …
rumen epithelium, plays critical roles in cellular growth and metabolism. The ketogenic …
[HTML][HTML] Hepatic nuclear factor kappa B signaling pathway and NLR family pyrin domain containing 3 inflammasome is over-activated in ketotic dairy cows
Ketosis is an important metabolic disease that can negatively affect the production efficiency
of dairy cows. Earlier studies have revealed metabolic and inflammatory alterations in the …
of dairy cows. Earlier studies have revealed metabolic and inflammatory alterations in the …
[HTML][HTML] Acetic acid influences BRL-3A cell lipid metabolism via the AMPK signalling pathway
L Li, M He, H **ao, X Liu, K Wang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Acetic acid (AcOH), a short-chain fatty acid, is reported to have some
beneficial effects on metabolism. Therefore, the aim of this study was to investigate the …
beneficial effects on metabolism. Therefore, the aim of this study was to investigate the …
[HTML][HTML] Hepatic autophagy and mitophagy status in dairy cows with subclinical and clinical ketosis
T Shen, F Xu, Z Fang, JJ Loor, H Ouyang, M Chen… - Journal of Dairy …, 2021 - Elsevier
Severe negative energy balance around parturition is an important contributor to ketosis, a
metabolic disorder that occurs most frequently in the peripartal period. Autophagy and …
metabolic disorder that occurs most frequently in the peripartal period. Autophagy and …
Choline and methionine regulate lipid metabolism via the AMPK signaling pathway in hepatocytes exposed to high concentrations of nonesterified fatty acids
High concentrations of nonesterified fatty acids (NEFAs) and β‐hydroxybutyric acid (BHBA)
induce lipid peroxidation, resulting in liver damage. Choline and methionine (Met) can …
induce lipid peroxidation, resulting in liver damage. Choline and methionine (Met) can …
[HTML][HTML] Liver transcriptome analysis reveals important factors involved in the metabolic adaptation of the transition cow
During early lactation, dairy cows experience a severe metabolic load often resulting in the
development of various diseases. The inevitable deficiency in nutrients and energy at the …
development of various diseases. The inevitable deficiency in nutrients and energy at the …
The role of tea tree oil in alleviating palmitic acid-induced lipid accumulation in bovine hepatocytes
T Yang, X Ma, M Jiang, Z Cheng… - Frontiers in Veterinary …, 2022 - frontiersin.org
Tea tree oil (TTO) plays an important role in lipid metabolism, alleviating the inflammatory
responses. Fatty liver is associated with lipid accumulation in hepatocytes, leading to …
responses. Fatty liver is associated with lipid accumulation in hepatocytes, leading to …