For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …

Trauma remains a leading cause of death worldwide. Hemorrhagic shock and direct injury to
vital organs are responsible for early mortality whereas most delayed deaths are secondary …

Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically
Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and …

Dr. Taylor disclosed serving as an ASPEN committee member and DNS past chair. Dr.
McClave disclosed other relationships with Nestle (consulting), Abbott (Speaker) …

Importance Sepsis is considered to induce immune suppression, leading to increased
susceptibility to secondary infections with associated late mortality. Objective To determine …

Here, we review a novel concept namely the compensatory immune-regulatory reflex system
(CIRS) as applied to the pathophysiology of major depressive disorder (MDD) and bipolar …

Although several dozen studies of gene expression in sepsis have been published,
distinguishing sepsis from a sterile systemic inflammatory response syndrome (SIRS) is still …

Objective: We hypothesized that after sepsis in humans, MDSCs will be persistently
increased, functionally immunosuppressive, and associated with adverse clinical outcomes …

Objective: The aim of this study was to identify the effects of recent innovations in trauma
major hemorrhage management on outcome and transfusion practice, and to determine the …

Background The nature of multiple organ dysfunction syndrome (MODS) after traumatic
injury is evolving as resuscitation practices advance and more patients survive their injuries …