In the brain, increases in neural activity drive changes in local blood flow via neurovascular
coupling. The common explanation for increased blood flow (known as functional …

Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow
(CBF). This review provides a practical guide and overview of the clinical applications of …

This report evaluates the scientific literature on caffeine with respect to potential
cardiovascular outcomes, specifically relative risks of total cardiovascular disease (CVD) …

OBJECTIVE: The beneficial effects of human caffeine consumption deserve clarification.
METHODS: A detailed literature review was conducted and summarized. RESULTS: A large …

Caffeine occurs naturally in various foods, such as coffee, tea, and cocoa, and it has been
used safely as a mild stimulant for a long time. However, excessive caffeine consumption …

Migraine is a chronic disorder, and caffeine has been linked with migraine for many years,
on the one hand as a trigger, and on the other hand as a cure. As most of the population …

Caffeinated headache medications, either alone or in combination with other treatments, are
widely used by patients with headache. Clinicians should be familiar with their use as well …

Improving cerebrovascular function may be a key mechanism whereby a healthy lifestyle, of
which a healthy diet combined with increased physical activity levels is a cornerstone …

Consumption of caffeine in the diet, both daily and occasional, has a significant biological
effect on the nervous system. Caffeine, through various and not yet fully investigated …

Accurate identification of brain function is necessary to understand the neurobiology of
cognitive ageing, and thereby promote well-being across the lifespan. A common tool used …