Proliferating cancer cells rely largely on glutamine for survival and proliferation. Glutamine
serves as a carbon source for the synthesis of lipids and metabolites via the TCA cycle, as …

Simple Summary Dysregulated glutamine metabolism is one of the metabolic features
evident in cancer cells when compared to normal cells. Cancer cells utilize glutamine for …

Cancer is characterized by metabolic reprogramming, which is a hot topic in tumor treatment
research. Cancer cells alter metabolic pathways to promote their growth, and the common …

Serine is a vital amino acid in tumorigenesis. While cells can perform de novo serine
synthesis, most transformed cells rely on serine uptake to meet their increased biosynthetic …

Cancer cells rely on certain extracellular nutrients to sustain their metabolism and growth.
Solute carrier (SLC) transporters enable cells to acquire extracellular nutrients or shuttle …

Metabolic alterations have been observed in many cancer types. The deregulated
metabolism has thus become an emerging hallmark of the disease, where the metabolism is …

Metastasis is the leading cause of colorectal cancer (CRC)-induced death. However, the
underlying molecular mechanisms of CRC metastasis are poorly understood. Metabolic …

There is no safe level of air pollution for human health. Traffic-related particulate matter (PM
2.5) is a major in-utero toxin, mechanisms of action of which are not fully understood. BALB/c …

Introduction: Oxidative stress (OS)-related genes have been confirmed to be closely related
to the prognosis of triple-negative breast cancer (TNBC) patients; despite this fact, there is …

Advances in cell metabolism over the past few decades have demonstrated glutamine as an
essential nutrient for cancer cell survival and proliferation. Glutamine offers a remarkable …