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[HTML][HTML] Live-attenuated bacterial vectors: tools for vaccine and therapeutic agent delivery
IYC Lin, TTH Van, PM Smooker - Vaccines, 2015 - mdpi.com
Genetically attenuated microorganisms, including pathogenic and commensal bacteria, can
be engineered to carry and deliver heterologous antigens to elicit host immunity against …
be engineered to carry and deliver heterologous antigens to elicit host immunity against …
The delicate balance in genetically engineering live vaccines
JE Galen, R Curtiss 3rd - Vaccine, 2014 - Elsevier
Contemporary vaccine development relies less on empirical methods of vaccine
construction, and now employs a powerful array of precise engineering strategies to …
construction, and now employs a powerful array of precise engineering strategies to …
Serotype-independent pneumococcal vaccines
Streptococcus pneumoniae remains an important cause of disease with high mortality and
morbidity, especially in children and in the elderly. The widespread use of the …
morbidity, especially in children and in the elderly. The widespread use of the …
Otitis media: recent advances in otitis media vaccine development and model systems
Otitis media is an inflammatory disorder of the middle ear caused by airways-associated
bacterial or viral infections. It is one of the most common childhood infections as globally …
bacterial or viral infections. It is one of the most common childhood infections as globally …
Salmonella vaccines: conduits for protective antigens
JE Clark-Curtiss, R Curtiss - The Journal of Immunology, 2018 - journals.aai.org
Vaccines afford a better and more cost-effective approach to combatting infectious diseases
than continued reliance on antibiotics or antiviral or antiparasite drugs in the current era of …
than continued reliance on antibiotics or antiviral or antiparasite drugs in the current era of …
S Wang, Q Kong, R Curtiss III - Microbial pathogenesis, 2013 - Elsevier
Recombinant attenuated Salmonella vaccine (RASV) vectors producing recombinant gene-
encoded protective antigens should have special traits. These features ensure that the …
encoded protective antigens should have special traits. These features ensure that the …
Salmonella Enterica As a Vaccine Carrier
WAH Hegazy, M Hensel - Future microbiology, 2012 - Taylor & Francis
Salmonella enterica is an invasive, facultative intracellular gastrointestinal pathogen
causing human diseases such as gastroenteritis and typhoid fever. Virulence-attenuated …
causing human diseases such as gastroenteritis and typhoid fever. Virulence-attenuated …
Salmonella as a vaccine delivery vehicle
KL Roland, KE Brenneman - Expert review of vaccines, 2013 - Taylor & Francis
Attenuated Salmonella vaccines can be administered orally to deliver recombinant antigens
to mucosal surfaces inducing a protective immune response against a variety of targeted …
to mucosal surfaces inducing a protective immune response against a variety of targeted …
Fur-regulated iron uptake system of Edwardsiella ictaluri and its influence on pathogenesis and immunogenicity in the catfish host
J Santander, G Golden, SY Wanda… - Infection and …, 2012 - journals.asm.org
The ability of bacterial pathogens to take up iron from the host during infection is necessary
for their multiplication within the host. However, host high-affinity iron binding proteins limit …
for their multiplication within the host. However, host high-affinity iron binding proteins limit …
Construction and Evaluation of an Efficient Live Attenuated Salmonella Choleraesuis Vaccine and Its Ability as a Vaccine Carrier to Deliver Heterologous Antigens
X Bian, J Chen, X Chen, C Liu, J Ding, M Li, X Zhang… - Vaccines, 2024 - mdpi.com
The gram-negative facultative intracellular pathogen Salmonella enterica serotype
Choleraesuis, also known as S. Choleraesuis, is a major financial loss for the pig business …
Choleraesuis, also known as S. Choleraesuis, is a major financial loss for the pig business …