Major depressive disorder (MDD) is one of the most prevalent psychiatric illnesses
worldwide which impairs the social functioning of the afflicted patients. Astrocytes promote …

Quantification of microglial activation through morphometric analysis has long been a staple
of the neuroimmunologist's toolkit. Microglial morphological phenomics can be conducted …

The function and regulation of different heterogeneous reactive states of astrocytes in
depression remain unclear. Here, we demonstrate that neurotoxic reactive (A1-like) …

Objectives Neuroinflammation has been suggested that affects the processing of
depression. There is renewed interest in berberine owing to its anti-inflammatory effects …

Background Regulating the microglial phenotype is an attractive strategy for treating
diseases of the central nervous system such as depression and anxiety. Gastrodin can …

Aggression and deficient cognitive control problems are widespread in psychiatric disorders,
including major depressive disorder (MDD). These abnormalities are known to contribute …

Naturally occurring flavonoids have long been utilized as essential templates for the
development of novel drugs and as critical ingredients for functional foods. Astragalin (AG) is …

The involvement of central and peripheral inflammation in the pathogenesis and prognosis
of major depressive disorder (MDD) has been demonstrated. The increase of pro …

Depression is a common mental disorder, the effective treatment of which remains a
challenging issue worldwide. The clinical pathogenesis of depression has been deeply …

Human epidemiological studies have identified links between nicotine intake and stress
disorders, including anxiety, depression and PTSD. Here we review the clinical evidence for …