Antiviral effects of interferon-stimulated genes in bats
D Zhang, AT Irving - Frontiers in Cellular and Infection Microbiology, 2023 - frontiersin.org
The interferon pathway is the first line of defense in viral infection in all mammals, and its
induction stimulates broad expression of interferon-stimulated genes (ISGs). In mice and …
induction stimulates broad expression of interferon-stimulated genes (ISGs). In mice and …
MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes
S Bottardi, T Layne, AC Ramòn, N Quansah… - Frontiers in …, 2024 - frontiersin.org
Inflammation control is critical during the innate immune response. Such response is
triggered by the detection of molecules originating from pathogens or damaged host cells by …
triggered by the detection of molecules originating from pathogens or damaged host cells by …
IFI207, a young and fast‐evolving protein, controls retroviral replication via the STING pathway
ABSTRACT Mammalian AIM-2-like receptor (ALR) proteins bind nucleic acids and initiate
production of type I interferons or inflammasome assembly, thereby contributing to host …
production of type I interferons or inflammasome assembly, thereby contributing to host …
Absent in Melanoma 2 Mediates Inflammasome Signaling Activation against Clostridium perfringens Infection
Z Ma, Y Lou, N Wang, Y Zhao, S Zhang… - International Journal of …, 2024 - mdpi.com
Absent in melanoma 2 (AIM2), a key component of the IFI20X/IFI16 (PYHIN) protein family, is
characterized as a DNA sensor to detect cytosolic bacteria and DNA viruses. However, little …
characterized as a DNA sensor to detect cytosolic bacteria and DNA viruses. However, little …
Ultrasound Mediated Mild Hyperthermia Resolves Neuroinflammation in an Animal Model
G Seasons - 2024 - prism.ucalgary.ca
Chronic neuroinflammation is an often overlooked aspect of the development of
neurodegenerative and autoimmune disease, especially in older populations, and there are …
neurodegenerative and autoimmune disease, especially in older populations, and there are …