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Immune response, inflammation, and the clinical spectrum of COVID-19
LF García - Frontiers in immunology, 2020 - frontiersin.org
The current COVID-19 pandemic began in December 2019 in Wuhan (China) and rapidly
extended to become a global sanitary and economic emergency. Its etiological agent is the …
extended to become a global sanitary and economic emergency. Its etiological agent is the …
SARS-CoV-2 pandemic and research gaps: Understanding SARS-CoV-2 interaction with the ACE2 receptor and implications for therapy
The COVID-19 pandemic is an emerging threat to global public health. While our current
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
understanding of COVID-19 pathogenesis is limited, a better understanding will help us …
[HTML][HTML] COVID-19 and individual genetic susceptibility/receptivity: role of ACE1/ACE2 genes, immunity, inflammation and coagulation. Might the double X …
In December 2019, a novel severe acute respiratory syndrome (SARS) from a new
coronavirus (SARS-CoV-2) was recognized in the city of Wuhan, China. Rapidly, it became …
coronavirus (SARS-CoV-2) was recognized in the city of Wuhan, China. Rapidly, it became …
The role of host genetics in the immune response to SARS‐CoV‐2 and COVID‐19 susceptibility and severity
IG Ovsyannikova, IH Haralambieva… - Immunological …, 2020 - Wiley Online Library
This article provides a review of studies evaluating the role of host (and viral) genetics
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …
(including variation in HLA genes) in the immune response to coronaviruses, as well as the …
Angiotensin-converting enzymes (ACE, ACE2) gene variants and COVID-19 outcome
J Gómez, GM Albaiceta, M García-Clemente… - Gene, 2020 - Elsevier
The Angiotensin system is implicated in the pathogenesis of COVID-19. First, ACE2 is the
cellular receptor for SARS-CoV-2, and expression of the ACE2 gene could regulate the …
cellular receptor for SARS-CoV-2, and expression of the ACE2 gene could regulate the …
[HTML][HTML] Severe respiratory SARS-CoV2 infection: Does ACE2 receptor matter?
SARS-CoV-2 is a novel virus of the Coronaviridiae family that represents a major global
health issue. Mechanisms implicated in virus/host cells interaction are central for cell …
health issue. Mechanisms implicated in virus/host cells interaction are central for cell …
COVID-19: Unique public health issues facing Black, Asian and minority ethnic communities
E Abuelgasim, LJ Saw, M Shirke, M Zeinah… - Current problems in …, 2020 - Elsevier
The 2019 coronavirus disease is a serious public health emergency, with serious adverse
implications for populations, healthcare systems, and economies globally. Recently …
implications for populations, healthcare systems, and economies globally. Recently …
The emerging role of ACE2 in physiology and disease
The renin–angiotensin–aldosterone system (RAAS) is a key regulator of systemic blood
pressure and renal function and a key player in renal and cardiovascular disease. However …
pressure and renal function and a key player in renal and cardiovascular disease. However …
The role of dysregulated immune responses in COVID-19 pathogenesis
Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …
Genetic variants of the human host influencing the coronavirus-associated phenotypes (SARS, MERS and COVID-19): rapid systematic review and field synopsis
The COVID-19 pandemic has strengthened the interest in the biological mechanisms
underlying the complex interplay between infectious agents and the human host. The …
underlying the complex interplay between infectious agents and the human host. The …