[HTML][HTML] Beta-caryophyllene, a cannabinoid receptor type 2 selective agonist, in emotional and cognitive disorders

C Ricardi, S Barachini, G Consoli, D Marazziti… - International journal of …, 2024 - mdpi.com
Mental disorders account for one of the most prevalent categories of the burden of disease
worldwide, with depression expected to be the largest contributor by 2030, closely followed …

Hypolipidemic activity of phytochemical combinations: A mechanistic review of preclinical and clinical studies

H Nechchadi, Y Nadir, K Benhssaine, C Alem… - Food Chemistry, 2024 - Elsevier
Hyperlipidemia, a condition characterized by elevated levels of lipids in the blood, poses a
significant risk factor for various health disorders, notably cardiovascular diseases …

Molecularly imprinted electrochemical sensor for determination of tetrahydrocannabinol in human blood plasma

Y Zhao, Y Moon, R Savari - International Journal of Electrochemical …, 2022 - Elsevier
The goal of this study was to create a molecular imprinting-based sensor on MWCNTs
modified electrode for the selective determination of Δ 9-tetrahydrocannabinol (Δ 9-THC) as …

Combined non-psychoactive Cannabis components cannabidiol and β-caryophyllene reduce chronic pain via CB1 interaction in a rat spinal cord injury model

A Eeswara, A Pacheco-Spiewak, S Jergova, J Sagen - PloS one, 2023 - journals.plos.org
The most frequently reported use of medical marijuana is for pain relief. However, its
psychoactive component Δ9-tetrahydrocannabinol (THC) causes significant side effects …

Multi-Target Approach of Murraya koenigii Leaves in Treating Neurodegenerative Diseases

MA Tan, N Sharma, SSA An - Pharmaceuticals, 2022 - mdpi.com
Neurodegenerative diseases (NDs) mainly affect neurons and gradually lead to a loss of
normal motor and cognitive functions. Atypical protein homeostasis—misfolding …

[HTML][HTML] Beta-caryophyllene, a plant-derived CB2 receptor agonist, protects SH-SY5Y cells from cadmium-induced toxicity

F Mannino, G Pallio, C Imbesi, A Scarfone… - International Journal of …, 2023 - mdpi.com
Cadmium (Cd) is a transition heavy metal that is able to accumulate in the central nervous
system and may induce cell death through reactive oxygen species (ROS)-mediated …

Chemical compositions and experimental and computational modeling of the anticancer effects of cnidocyte venoms of jellyfish Cassiopea andromeda and Catostylus …

A Zare, A Afshar, A Khoradmehr, N Baghban… - Marine Drugs, 2023 - mdpi.com
Nowadays, major attention is being paid to curing different types of cancers and is focused
on natural resources, including oceans and marine environments. Jellyfish are marine …

Cannabinoids and sleep: exploring biological mechanisms and therapeutic potentials

M D'Angelo, L Steardo Jr - International Journal of Molecular Sciences, 2024 - mdpi.com
The endogenous cannabinoid system (ECS) plays a critical role in the regulation of various
physiological functions, including sleep, mood, and neuroinflammation. Phytocannabinoids …

Beta-caryophyllene exhibits anti-proliferative effects through apoptosis induction and cell cycle modulation in multiple myeloma cells

F Mannino, G Pallio, R Corsaro, L Minutoli, D Altavilla… - Cancers, 2021 - mdpi.com
Cannabinoid receptors, which are widely distributed in the body, have been considered as
possible pharmacological targets for the management of several tumors. Cannabinoid type …

[HTML][HTML] β-Caryophyllene Inhibits Oxaliplatin-Induced Peripheral Neuropathy in Mice: Role of Cannabinoid Type 2 Receptors, Oxidative Stress and Neuroinflammation

JP Agnes, B Dos Santos, RN das Neves, VMM Luciano… - Antioxidants, 2023 - mdpi.com
Peripheral neuropathy is an important adverse effect caused by some chemotherapeutic
agents, including oxaliplatin (OXA). OXA-induced peripheral neuropathy (OIPN) is a …