Perspective: Vitamin D deficiency and COVID‐19 severity–plausibly linked by latitude, ethnicity, impacts on cytokines, ACE2 and thrombosis

JM Rhodes, S Subramanian, E Laird… - Journal of internal …, 2021 - Wiley Online Library
Background SARS‐CoV‐2 coronavirus infection ranges from asymptomatic through to fatal
COVID‐19 characterized by a 'cytokine storm'and lung failure. Vitamin D deficiency has …

Inflammaging as a target for healthy ageing

B Dugan, J Conway, NA Duggal - Age and ageing, 2023 - academic.oup.com
Life expectancy has been on the rise for the past few decades, but healthy life expectancy
has not kept pace, leading to a global burden of age-associated disorders. Advancing age is …

[PDF][PDF] Vitamin D and inflammation: potential implications for severity of Covid-19

E Laird, J Rhodes, RA Kenny - Ir Med J, 2020 - researchgate.net
Background Vitamin D is a micronutrient which is essential to help maintain bone and
musculoskeletal health1. However, recent research has highlighted a crucial supportive role …

[HTML][HTML] Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition

PC Calder, N Bosco, R Bourdet-Sicard, L Capuron… - Ageing research …, 2017 - Elsevier
Ageing of the global population has become a public health concern with an important socio-
economic dimension. Ageing is characterized by an increase in the concentration of …

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

M Puzianowska-Kuźnicka, M Owczarz… - Immunity & …, 2016 - Springer
Background In the elderly, chronic low-grade inflammation (inflammaging) is a risk factor for
the development of aging-related diseases and frailty. Using data from several thousand …

Impact of vitamin D supplementation on influenza vaccine response and immune functions in deficient elderly persons: a randomized placebo-controlled trial

N Goncalves-Mendes, J Talvas, C Dualé… - Frontiers in …, 2019 - frontiersin.org
Background: Immunosenescence contributes to reduced vaccine response in elderly
persons, and is worsened by deficiencies in nutrients such as Vitamin (Vit-D). The immune …

Clinical and metabolic response to vitamin D plus probiotic in schizophrenia patients

A Ghaderi, HR Banafshe, N Mirhosseini, M Moradi… - BMC psychiatry, 2019 - Springer
Background This study determined the effects of a novel combination of vitamin D and
probiotic on metabolic and clinical symptoms in chronic schizophrenia. Methods This trial …

Efficacy of vitamin D supplementation as an adjunct therapy for improving inflammatory and oxidative stress biomarkers: An umbrella meta-analysis

E Moslemi, V Musazadeh, Z Kavyani, N Naghsh… - Pharmacological …, 2022 - Elsevier
Background Vitamin D supplementation has attracted a lot of attention as a potential
modulator of inflammation and oxidative stress, while some studies have reported …

Gender differences in the interplay between vitamin D and microbiota in allergic and autoimmune diseases

G Murdaca, L Tagliafico, E Page, F Paladin, S Gangemi - Biomedicines, 2024 - mdpi.com
The synergic role of vitamin D and the intestinal microbiota in the regulation of the immune
system has been thoroughly described in the literature. Vitamin D deficiency and intestinal …

[HTML][HTML] Altered immune system in frailty: genetics and diet may influence inflammation

O Pansarasa, C Pistono, A Davin, M Bordoni… - Ageing research …, 2019 - Elsevier
Frailty is a complex geriatric syndrome associated with biological vulnerability to stressors
and decreased physiological reserve. Its etiology and pathogenesis are not completely …