The advancing validation and exploitation of CSF and blood neurofilament light chain
protein as a biomarker of neuroaxonal damage has deeply changed the current diagnostic …

Numerous studies have begun to address how the brain's gray and white matter may be
shaped by meditation. This research is yet to be integrated, however, and two fundamental …

Despite decades of research, the pathophysiology of bipolar disorder (BD) is still not well
understood. Structural brain differences have been associated with BD, but results from …

Finding robust brain substrates of mood disorders is an important target for research. The
degree to which major depression (MDD) and bipolar disorder (BD) are associated with …

Considerable uncertainty exists about the defining brain changes associated with bipolar
disorder (BD). Understanding and quantifying the sources of uncertainty can help generate …

Mood disorders have been recognized by the World Health Organization (WHO) as the
leading cause of disability worldwide. Notwithstanding the established efficacy of …

Objective An association between bipolar disorder and cognitive impairment has repeatedly
been described, even for euthymic patients. Findings are inconsistent both across primary …

Purpose There is a growing amount of evidence to suggest that inflammation may have a
role in the onset and prognosis of psychiatric disorders. We reviewed the literature of studies …

Objectives Research with mindfulness-based programs (MBPs) has found participating in an
MBP to predict beneficial outcomes; however, there is currently mixed research regarding …

Context Although differences in clinical characteristics exist between major depressive
disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that …