Tandem repeats lead to sequence assembly errors and impose multi-level challenges for genome and protein databases

OK Tørresen, B Star, P Mier… - Nucleic acids …, 2019 - academic.oup.com
The widespread occurrence of repetitive stretches of DNA in genomes of organisms across
the tree of life imposes fundamental challenges for sequencing, genome assembly, and …

Overcoming Fish Defences: The Virulence Factors of Yersinia ruckeri

A Wrobel, JC Leo, D Linke - Genes, 2019 - mdpi.com
Yersinia ruckeri is the causative agent of enteric redmouth disease, a bacterial infection of
marine and freshwater fish. The disease mainly affects salmonids, and outbreaks have …

Metabolic and genetic basis for auxotrophies in Gram-negative species

Y Seif, KS Choudhary, Y Hefner… - Proceedings of the …, 2020 - National Acad Sciences
Auxotrophies constrain the interactions of bacteria with their environment, but are often
difficult to identify. Here, we develop an algorithm (AuxoFind) using genome-scale metabolic …

Effect of glyphosate, its metabolite AMPA, and the glyphosate formulation Roundup® on brown trout (Salmo trutta f. fario) gut microbiome diversity

N Hembach, V Drechsel, M Sobol, AK Kaster… - Frontiers in …, 2024 - frontiersin.org
Glyphosate is used worldwide as a compound of pesticides and is detectable in many
environmental compartments. It enters water bodies primarily through drift from agricultural …

RTX adhesins are key bacterial surface megaproteins in the formation of biofilms

S Guo, TDR Vance, CA Stevens, I Voets… - Trends in microbiology, 2019 - cell.com
Gram-negative bacteria produce repeats-in-toxin adhesion proteins (RTX adhesins) to
facilitate microbial adhesion. These large, multidomain proteins share a common …

The Infection Process of Yersinia ruckeri: Reviewing the Pieces of the Jigsaw Puzzle

JA Guijarro, AI García-Torrico, D Cascales… - Frontiers in cellular and …, 2018 - frontiersin.org
Finding the keys to understanding the infectious process of Yersinia ruckeri was not a
priority for many years due to the prompt development of an effective biotype 1 vaccine …

The inverse autotransporters of Yersinia ruckeri, YrInv and YrIlm, contribute to biofilm formation and virulence

A Wrobel, A Saragliadis, J Pérez‐Ortega… - Environmental …, 2020 - Wiley Online Library
Yersinia ruckeri causes enteric redmouth disease (ERM) that mainly affects salmonid fishes
and leads to significant economic losses in the aquaculture industry. An increasing number …

[HTML][HTML] Comparative bioinformatic and proteomic approaches to evaluate the outer membrane proteome of the fish pathogen Yersinia ruckeri

MJ Ormsby, E Grahame, R Burchmore, RL Davies - Journal of proteomics, 2019 - Elsevier
Yersinia ruckeri is the aetiological agent of enteric redmouth (ERM) disease and is
responsible for significant economic losses in farmed salmonids. Enteric redmouth disease …

Fish pathogen binding to mucins from Atlantic salmon and Arctic char differs in avidity and specificity and is modulated by fluid velocity

JT Padra, AVM Murugan, K Sundell, H Sundh… - PloS one, 2019 - journals.plos.org
Disease outbreaks are limiting factors for an ethical and economically sustainable
aquaculture industry. The first point of contact between a pathogen and a host occurs in the …

Host-pathogen adhesion as the basis of innovative diagnostics for emerging pathogens

A van Belkum, C Almeida, B Bardiaux, SV Barrass… - Diagnostics, 2021 - mdpi.com
Infectious diseases are an existential health threat, potentiated by emerging and re-
emerging viruses and increasing bacterial antibiotic resistance. Targeted treatment of …