Wine, and particularly red wine, is a beverage with a great chemical complexity that is in
continuous evolution. Chemically, wine is a hydroalcoholic solution (~ 78% water) that …

Gallic acid (3, 4, 5-trihydroxybenzoic acid) is a phenolic acid widely distributed in many
different families of higher plants, both in free state, and as a part of more complex …

Scope Grape seed polyphenol extract (GSPE) is receiving increasing attention for its
potential preventative and therapeutic roles in Alzheimer's disease (AD) and other age …

Alzheimer's disease (AD) is a progressive, neurodegenerative disease characterized by
extracellular β-amyloid (Aβ) plaques and intracellular neurofibrillary tangles in the brain. Aβ …

Marine environment has proven to be a rich source of structurally diverse and complex
compounds exhibiting numerous interesting biological effects. Macroalgae are currently …

Purpose Resveratrol is a polyphenol present in red wine for which the capability of directly
interfering with the hallmark of Alzheimer's disease (AD), ie toxic β-amyloid protein (Aβ) …

There is little doubt that we are what we eat. Fatty acid supplementation and diets rich in fatty
acids are being promoted as ways to a healthier brain. Short chain fatty acids are a product …

Resveratrol is a natural phytoestrogen with neuroprotective properties. Polyphenolic
compounds including resveratrol exert in vitro antioxidant, anti‐inflammatory, and …

Oxidative Stress (OS) produces the formation of free radicals and other reactive oxygen and
nitrogen species that are intimately involved in many diseases, especially Chronic …

Neurodegenerative diseases cause a progressive functional alteration of neuronal systems,
resulting in a state of dementia which is considered one of the most common psychiatric …