Compartmentalization of the aqueous space within a cell is necessary for life. In similar
fashion to the nanometer-scale compartments in living systems, synthetic water-soluble …

The study of the interactions of salts and osmolytes with macromolecules in aqueous
solution originated with experiments concerning protein precipitation more than 100 years …

The optical, electronic, and mechanical properties of graphite, few-layer, and two-
dimensional (2D) materials have prompted a considerable number of applications …

The aversion of hydrophobic solutes for water drives diverse interactions and assemblies
across materials science, biology, and beyond. Here, we review the theoretical …

The emergent properties that arise from self-assembly and molecular recognition
phenomena are a direct consequence of non-covalent interactions. Gas-phase …

Hydrophobicity is often characterized macroscopically by the droplet contact angle.
Molecular signatures of hydrophobicity have, however, remained elusive. Successful …

We have studied the hydrophobic water/octadecyltrichlorosilane (OTS) interface by using
the phase-sensitive sum-frequency vibrational spectroscopy (PS-SFVS), and we obtained …

Understanding and predicting the behavior of water, especially in contact with various
surfaces, is a scientific challenge. Molecular-level understanding of hydrophobic effects and …

The direct binding mechanism for urea-based denaturation of proteins was tested with a
thermoresponsive polymer, poly (N-isopropylacrylamide)(PNIPAM). Thermodynamic …

Macroscopic characterizations of hydrophobicity (eg, contact angle measurements) do not
extend to the surfaces of proteins and nanoparticles. Molecular measures of hydrophobicity …