Almost all polymerase II transcripts undergo alternative pre-mRNA splicing. Here, we review
the functions of alternative splicing events that have been experimentally determined. The …

One of the fundamental issues in RNA splicing research is represented by understanding
how the spliceosome can successfully define exons and introns in a huge variety of pre …

Plants have adapted to tolerate and survive constantly changing environmental conditions
by reprogramming gene expression The dynamics of the contribution of alternative splicing …

Spinal muscular atrophy (SMA), a prominent genetic disease of infant mortality, is caused by
low levels of survival motor neuron (SMN) protein owing to deletions or mutations of the …

Plants, like animals, are constantly exposed to abiotic and biotic stresses, which often inhibit
plant growth and development, and cause tissue damage, disease, and even plant death …

UHMK1, a serine/threonine kinase with a U2AF homology motif, is implicated in RNA
processing and protein phosphorylation. Increasing evidence has indicated its involvement …

While inflammation induced by Toll-like receptor (TLR) signaling is required to combat
infection, persistent inflammation can damage host tissues and contribute to a myriad of …

Background Dysregulations in alternative splicing (AS) patterns have been associated with
many human diseases including cancer. In the present study, alterations to the global RNA …

The past decades have witnessed a surge of discoveries revealing RNA regulation as a
central player in cellular processes. RNAs are regulated by RNA-binding proteins (RBPs) at …

Although a robust inflammatory response is needed to combat infection, this response must
ultimately be terminated to prevent chronic inflammation. One mechanism that terminates …