Background Lung diseases including chronic obstructive pulmonary disease (COPD),
infections like influenza, acute respiratory distress syndrome (ARDS), asthma and …

Oral inhalation is the preferred route for delivery of small molecules to the lungs, because
high tissue levels can be achieved shortly after application. Biologics are mainly …

Neutrophils have a critical role in the innate immune response to infection and the control of
inflammation. A key component of this process is the release of neutrophil serine proteases …

Aerosolization of immunotherapies poses incredible potential for manipulating the local
mucosal-specific microenvironment, engaging specialized pulmonary cellular defenders …

Biologic therapeutics such as protein/polypeptide drugs are conventionally administered
systemically via intravenous injection for the treatment of diseases including lung diseases …

The rising demand for novel cosmeceutical ingredients has highlighted peptides as a
significant category. Based on the collagen turnover modulation properties of SA1-III, a …

Common airborne allergens (pollen, animal dander and those from fungi and insects) are
the main triggers of type I allergic disorder in the respiratory system and are associated with …

Quorum sensing (QS) is a system of bacteria in which cells communicate with each other; it
is linked to cell density in the microbiome. The high-density colony population can provide …

Trypsin-like proteases (TLPs) belong to a family of serine enzymes with primary substrate
specificities for the basic residues, lysine and arginine, in the P1 position. Whilst initially …

Abstract Purpose of Review Lung fibrosis is currently thought to stem from an aberrant
wound healing response after recurring (micro) injuries in the lung epithelium, together with …