Atherosclerosis is a chronic inflammatory disease that arises from an imbalance in lipid
metabolism and a maladaptive immune response driven by the accumulation of cholesterol …

Genetic factors contribute importantly to the risk of coronary artery disease (CAD), and in the
past decade, there has been major progress in this area. The tools applied include genome …

Cardiovascular disease (CVD) accounts for almost half of all deaths related to non-
communicable disease worldwide, making it the single largest global cause of mortality …

Atherosclerosis is characterized by the retention of modified lipoproteins in the arterial wall.
These modified lipoproteins activate resident macrophages and the recruitment of monocyte …

Objective—During inflammation, macrophages secrete vesicles carrying RNA, protein, and
lipids as a form of extracellular communication. In the vessel wall, extracellular vesicles …

Atherosclerosis, a chronic lipid-driven inflammatory disease affecting large arteries,
represents the primary cause of cardiovascular disease in the world. The local remodeling of …

Atherosclerosis is a complex chronic disease. The accumulation of myeloid cells in the
arterial intima, including macrophages and dendritic cells (DCs), is a feature of early stages …