Biodegradable polymer nanogels for drug/nucleic acid delivery

Y Li, D Maciel, J Rodrigues, X Shi, H Tomás - Chemical reviews, 2015 - ACS Publications
Despite the extensive research on therapeutic delivery, many problems still exist on how to
develop a proper platform (a carrier) that can deliver drugs/nucleic acids to specific sites of …

Progress and prospects of polysaccharide-based nanocarriers for oral delivery of proteins/peptides

H Yuan, C Guo, L Liu, L Zhao, Y Zhang, T Yin… - Carbohydrate …, 2023 - Elsevier
The oral route has long been recognized as the most preferred route for drug delivery as it
offers high patient compliance and requires minimal expertise. Unlike small molecule drugs …

Parameters influencing the size of chitosan-TPP nano-and microparticles

S Sreekumar, FM Goycoolea, BM Moerschbacher… - Scientific reports, 2018 - nature.com
Chitosan nanoparticles, produced by ionic gelation, are among the most intensely studied
nanosystems for drug delivery. However, a lack of inter-laboratory reproducibility and a poor …

Study on the relationship between crosslinking degree and properties of TPP crosslinked chitosan nanoparticles

C Pan, J Qian, C Zhao, H Yang, X Zhao, H Guo - Carbohydrate Polymers, 2020 - Elsevier
In order to reveal the relationship between the degree of crosslinking and the properties of
chitosan nanoparticles, a potassium polyvinyl sulfate (PVSK) titration method was …

Preparation of chitosan nanoparticles by ionotropic gelation technique: Effects of formulation parameters and in vitro characterization

SA Algharib, A Dawood, K Zhou, D Chen, C Li… - Journal of Molecular …, 2022 - Elsevier
Abstract Chitosan (CS) nanoparticles (NPs) prepared by ionotropic gelation technique are
one of the forcefully studied nanosystems used for drug delivery. Though, a deficiency of …

Polysaccharide-based nanogels for biomedical applications: A comprehensive review

F Damiri, S Rojekar, Y Bachra, RS Varma… - Journal of Drug Delivery …, 2023 - Elsevier
The biomedical, biotech, and food industries all use polysaccharides as vital biomolecules
with a variety of applications. Polysaccharides have a great deal of potential as biomaterials …

Physicochemical and morphological properties of size-controlled chitosan–tripolyphosphate nanoparticles

J Antoniou, F Liu, H Majeed, J Qi, W Yokoyama… - Colloids and Surfaces A …, 2015 - Elsevier
Chitosan–tripolyphosphate nanoparticles have been extensively studied during the last
decade because of their numerous applications. In this study, we describe conditions to …

Stability of chitosan nanoparticles cross-linked with tripolyphosphate

H Jonassen, AL Kjøniksen, M Hiorth - Biomacromolecules, 2012 - ACS Publications
The physical stability of chitosan nanoparticles cross-linked with sodium tripolyphosphate
(TPP) was investigated over a period of 1 month. Special emphasis was placed on changes …

Adsorption of three selected pharmaceuticals and personal care products (PPCPs) onto MIL-101 (Cr)/natural polymer composite beads

N Zhuo, Y Lan, W Yang, Z Yang, X Li, X Zhou… - Separation and …, 2017 - Elsevier
Porous metal-organic frameworks (MOFs) have great potential as high-effective adsorbents
for water treatment. However, poor separability restricts their practical application. To …

Isothermal titration calorimetry (ITC) as a promising tool in pharmaceutical nanotechnology

IDL Cavalcanti, FHX Junior, NSS Magalhães… - International Journal of …, 2023 - Elsevier
Isothermal titration calorimetry (ITC) is a technique for evaluating the thermodynamic profiles
of connection between two molecules, allowing the experimental design of nanoparticles …