The tumor microenvironment is a heterogeneous population of cells consisting of the tumor
bulk plus supporting cells. It is becoming increasingly evident that these supporting cells are …

Angiogenesis is a critical process required for tumor progression. Newly formed blood
vessels provide nutrition and oxygen to the tumor contributing to its growth and …

Over the past 5 years, the advent of combination therapeutic strategies has substantially
reshaped the clinical management of patients with advanced prostate cancer. However …

Our understanding of prostate cancer (PCa) has shifted from solely caused by a few genetic
aberrations to a combination of complex biochemical dysregulations with the prostate …

Simple Summary Biochemical inhibition of male sex hormone function (androgen signaling),
also known as androgen deprivation therapy (ADT), for human prostate cancer remains a …

Immunotherapy is currently regarded as the most promising treatment to fight against
cancer. This is particularly true in the treatment of chronic lymphocytic leukemia, an indolent …

Prostate cancer is a serious disease that endangers men's health. The genetic mechanism
and treatment of prostate cancer have attracted the attention of scientists. In this paper, we …

Olfactory receptor OR51E2, also known as a Prostate Specific G-Protein Receptor, is highly
expressed in prostate cancer but its function is not well understood. Through in silico and in …

Lineage transformation between lung cancer subtypes is a poorly understood phenomenon
associated with resistance to treatment and poor patient outcomes. Here, we aimed to model …

The increasing potency of therapies that target the androgen receptor (AR) signalling axis
has correlated with a rise in the proportion of patients with prostate cancer harbouring an …