The last decade has witnessed unparalleled advances in our understanding of the
complexity of the oral microbiome and the compositional changes that occur in subgingival …

Objective Clinical gingival inflammation is a well‐defined site‐specific condition for which
several measurement systems have been proposed and validated, and epidemiological …

Bone remodeling is tightly controlled by osteoclast-mediated bone resorption and osteoblast-
mediated bone formation. Fine tuning of the osteoclast–osteoblast balance results in strict …

Abstract Interleukin (IL)-1β, a pro-inflammatory cytokine, was elevated and participates in
periodontitis. Not only the link between IL-1β and periodontitis was proved by clinical …

The methodologies applicable for the evaluation of periodontal associated diseases are
constantly evolving to provide quick, realistic, and scientifically proven results. Trends in the …

Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key
clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host …

In evaluating the pathogenesis of periodontal diseases, the diagnostic potential of gingival
crevicular fluid has been extensively explored during the last twenty years, from initially just …

Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival
crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of …

Periodontal diseases are highly prevalent chronic diseases, and severe periodontitis
creates functional and esthetic problems and decreases self‐esteem for a large percentage …

In the era of personalized/precision health care, additional effort is being expended to
understand the biology and molecular mechanisms of disease processes. How these …