The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment

AH Ashok, TR Marques, S Jauhar, MM Nour… - Molecular …, 2017 - nature.com
Bipolar affective disorder is a common neuropsychiatric disorder. Although its
neurobiological underpinnings are incompletely understood, the dopamine hypothesis has …

Beyond the association. Toxoplasma gondii in schizophrenia, bipolar disorder, and addiction: systematic review and meta‐analysis

AL Sutterland, G Fond, A Kuin… - Acta Psychiatrica …, 2015 - Wiley Online Library
Objective To perform a meta‐analysis on studies reporting prevalence of T oxoplasma
gondii (T. gondii) infection in any psychiatric disorder compared with healthy controls. Our …

Reward processing and mood-related symptoms: An RDoC and translational neuroscience perspective

R Nusslock, LB Alloy - Journal of affective disorders, 2017 - Elsevier
Background Two objectives of the NIMH Research Domain Criteria (RDoC) initiative are to
identify (a) mechanisms that are common to multiple psychiatric disorders, and (b) …

[HTML][HTML] Clinical trials of N-acetylcysteine in psychiatry and neurology: a systematic review

J Slattery, N Kumar, L Delhey, M Berk, O Dean… - Neuroscience & …, 2015 - Elsevier
N-acetylcysteine (NAC) is recognized for its role in acetaminophen overdose and as a
mucolytic. Over the past decade, there has been growing evidence for the use of NAC in …

Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors

M Berk, F Kapczinski, AC Andreazza, OM Dean… - … & biobehavioral reviews, 2011 - Elsevier
There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

An oldie but goodie: lithium in the treatment of bipolar disorder through neuroprotective and neurotrophic mechanisms

E Won, YK Kim - International journal of molecular sciences, 2017 - mdpi.com
Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …

Potential mechanisms of action of lithium in bipolar disorder: Current understanding

GS Malhi, M Tanious, P Das, CM Coulston, M Berk - CNS drugs, 2013 - Springer
Lithium has been used for over half a century for the treatment of bipolar disorder as the
archetypal mood stabilizer, and has a wealth of empirical evidence supporting its efficacy in …

Sleep disturbance as transdiagnostic: consideration of neurobiological mechanisms

AG Harvey, G Murray, RA Chandler… - Clinical psychology review, 2011 - Elsevier
Sleep disturbance is increasingly recognized as an important, but understudied, mechanism
in the complex and multi-factorial causation of the symptoms and functional disability …

Biological hypotheses and biomarkers of bipolar disorder

E Sigitova, Z Fišar, J Hroudová… - Psychiatry and …, 2017 - Wiley Online Library
The most common mood disorders are major depressive disorders and bipolar disorders
(BD). The pathophysiology of BD is complex, multifactorial, and not fully understood …

Integrated neurobiology of bipolar disorder

V Maletic, C Raison - Frontiers in psychiatry, 2014 - frontiersin.org
From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …