Bone remodeling replaces old and damaged bone with new bone through a sequence of
cellular events occurring on the same surface without any change in bone shape. It was …

Bone remodeling is a lifelong process that gives rise to a mature, dynamic bone structure via
a balance between bone formation by osteoblasts and resorption by osteoclasts. These …

The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …

C-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of
receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a …

Diabetic osteoporosis (DOP) is the leading complication continuously threatening the bone
health of patients with diabetes. A key pathogenic factor in DOP is loss of osteocyte viability …

Since the proposal of Paul Ehrlich's magic bullet concept over 100 years ago, tremendous
advances have occurred in targeted therapy. From the initial selective antibody, antitoxin to …

Humans are spending an increasing amount of time in space, where exposure to conditions
of microgravity causes 1–2% bone loss per month in astronauts. Through data collected …

Ferroptosis is a necrotic form of iron‐dependent regulatory cell death. Estrogen withdrawal
can interfere with iron metabolism, which is responsible for the pathogenesis of …

Reproductive hormones play a crucial role in the growth and maintenance of the
mammalian skeleton. Indeed, the biological significance for this hormonal regulation of …

In the field of bone defect repair, 3D printed scaffolds have the characteristics of
personalized customization and accurate internal structure. However, how to construct a …