Interplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization

AN Istrate, SA Kozin, SS Zhokhov, AB Mantsyzov… - Scientific Reports, 2016 - nature.com
Conformational changes of Aβ peptide result in its transformation from native monomeric
state to the toxic soluble dimers, oligomers and insoluble aggregates that are hallmarks of …

Roles of zinc ions and structural polymorphism of β-amyloid in the development of Alzheimer's disease

AA Kulikova, AA Makarov, SA Kozin - Molecular Biology, 2015 - Springer
Aggregation of the β-amyloid peptide (Aβ) underlies the development of Alzheimer's
disease. The review considers the main steps of the Aβ formation and aggregation …

NMR solution structure of rat Aβ (1–16): toward understanding the mechanism of rats' resistance to Alzheimer's disease

AN Istrate, PO Tsvetkov, AB Mantsyzov, AA Kulikova… - Biophysical journal, 2012 - cell.com
In an attempt to reveal the mechanism of rats' resistance to Alzheimer's disease, we
determined the structure of the metal-binding domain 1–16 of rat β-amyloid (rat Aβ (1–16)) in …

Identification of a new small bioactive peptide from Lactobacillus gasseri supernatant

A Zanfardino, G Criscuolo, B Di Luccia… - Beneficial …, 2017 - wageningenacademic.com
Ten lactic acid bacteria (LAB) strains, previously isolated from human ileal biopsy of healthy
volunteers, were screened for production and secretion of molecules having anti-bacterial …