Bacteria produce a wide range of exopolysaccharides which are synthesized via different
biosynthesis pathways. The genes responsible for synthesis are often clustered within the …

Many infectious diseases in humans are caused or exacerbated by biofilms. Dental caries is
a prime example of a biofilm-dependent disease, resulting from interactions of …

Abstract α-Amylase (EC 3.2. 1.1) represents the best known amylolytic enzyme. It catalyzes
the hydrolysis of α-1, 4-glucosidic bonds in starch and related α-glucans. In general, the α …

Bacteria have acquired sophisticated mechanisms for assembling and disassembling
polysaccharides of different chemistry. α-d-Glucose homopolysaccharides, so-called α …

Candida albicans is frequently detected with heavy infection by Streptococcus mutans in
plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm …

Glucansucrases are extracellular enzymes that synthesize a wide variety of α-glucan
polymers and oligosaccharides, such as dextran. These carbohydrates have found …

The oral cavity contains a rich consortium of exopolysaccharide-producing microbes. These
extracellular polysaccharides comprise a major component of the oral biofilm. Together with …

Carbohydrates are ubiquitous in Nature and play vital roles in many biological systems.
Therefore the synthesis of carbohydrate-based compounds is of considerable interest for …

Dental plaque biofilms are responsible for numerous chronic oral infections and cause a
severe health burden. Many of these infections cannot be eliminated, as the bacteria in the …

Transglucosidases belonging to the glycoside hydrolase (GH) family 70 are promising
enzymatic tools for the synthesis of α-glucans with defined structures from renewable …