[HTML][HTML] Artificial intelligence for COVID-19: Battling the pandemic with computational intelligence
The new coronavirus disease 2019 (COVID-19) has become a global pandemic leading to
over 180 million confirmed cases and nearly 4 million deaths until June 2021, according to …
over 180 million confirmed cases and nearly 4 million deaths until June 2021, according to …
Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts
Background Patients with COVID-19-related acute respiratory distress syndrome (ARDS)
have been postulated to present with distinct respiratory subphenotypes. However, most …
have been postulated to present with distinct respiratory subphenotypes. However, most …
Clinical sepsis phenotypes in critically ill patients
G Papathanakos, I Andrianopoulos, M Xenikakis… - Microorganisms, 2023 - mdpi.com
Sepsis, defined as the life-threatening dysregulated host response to an infection leading to
organ dysfunction, is considered as one of the leading causes of mortality worldwide …
organ dysfunction, is considered as one of the leading causes of mortality worldwide …
Development and validation of novel sepsis subphenotypes using trajectories of vital signs
Purpose Sepsis is a heterogeneous syndrome and identification of sub-phenotypes is
essential. This study used trajectories of vital signs to develop and validate sub-phenotypes …
essential. This study used trajectories of vital signs to develop and validate sub-phenotypes …
Comparing clinical features and outcomes in mechanically ventilated patients with COVID-19 and acute respiratory distress syndrome
Rationale: Patients with severe coronavirus disease (COVID-19) meet clinical criteria for the
acute respiratory distress syndrome (ARDS), yet early reports suggested they differ …
acute respiratory distress syndrome (ARDS), yet early reports suggested they differ …
The gut microbiome modulates body temperature both in sepsis and health
KS Bongers, R Chanderraj, RJ Woods… - American Journal of …, 2023 - atsjournals.org
Rationale: Among patients with sepsis, variation in temperature trajectories predicts clinical
outcomes. In healthy individuals, normal body temperature is variable and has decreased …
outcomes. In healthy individuals, normal body temperature is variable and has decreased …
Analysis of protein biomarkers from hospitalized COVID-19 patients reveals severity-specific signatures and two distinct latent profiles with differential responses to …
PA Verhoef, AB Spicer, C Lopez-Espina… - Critical care …, 2023 - journals.lww.com
OBJECTIVES: To identify and validate novel COVID-19 subphenotypes with potential
heterogenous treatment effects (HTEs) using electronic health record (EHR) data and 33 …
heterogenous treatment effects (HTEs) using electronic health record (EHR) data and 33 …
Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial
Purpose Latent class analysis (LCA) has identified hyper-and non-hyper-inflammatory
subphenotypes in patients with acute respiratory distress syndrome (ARDS). It is unknown …
subphenotypes in patients with acute respiratory distress syndrome (ARDS). It is unknown …
Distinct immune profiles and clinical outcomes in sepsis subphenotypes based on temperature trajectories
SV Bhavani, A Spicer, P Sinha, A Malik… - Intensive care …, 2024 - Springer
Purpose Sepsis is a heterogeneous syndrome. Identification of sepsis subphenotypes with
distinct immune profiles could lead to targeted therapies. This study investigates the immune …
distinct immune profiles could lead to targeted therapies. This study investigates the immune …
[HTML][HTML] Severe acute respiratory syndrome–associated coronavirus 2 infection and organ dysfunction in the ICU: Opportunities for translational research
PA Verhoef, S Kannan, JL Sturgill… - Critical care …, 2021 - journals.lww.com
Objectives: Since the beginning of the coronavirus disease 2019 pandemic, hundreds of
thousands of patients have been treated in ICUs across the globe. The severe acute …
thousands of patients have been treated in ICUs across the globe. The severe acute …