Interferon-inducible effector mechanisms in cell-autonomous immunity
JD MacMicking - Nature Reviews Immunology, 2012 - nature.com
Interferons (IFNs) induce the expression of hundreds of genes as part of an elaborate
antimicrobial programme designed to combat infection in all nucleated cells—a process …
antimicrobial programme designed to combat infection in all nucleated cells—a process …
malERA: an updated research agenda for malaria elimination and eradication
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …
overwhelming health, equity, and economic benefits. WHO and countries are setting …
Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease
PD Crompton, J Moebius, S Portugal… - Annual review of …, 2014 - annualreviews.org
Malaria is a mosquito-borne disease caused by parasites of the obligate intracellular
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …
Tick immune system: what is known, the interconnections, the gaps, and the challenges
AC Fogaça, G Sousa, DB Pavanelo, E Esteves… - Frontiers in …, 2021 - frontiersin.org
Ticks are ectoparasitic arthropods that necessarily feed on the blood of their vertebrate
hosts. The success of blood acquisition depends on the pharmacological properties of tick …
hosts. The success of blood acquisition depends on the pharmacological properties of tick …
Mosquito innate immunity
Mosquitoes live under the endless threat of infections from different kinds of pathogens such
as bacteria, parasites, and viruses. The mosquito defends itself by employing both physical …
as bacteria, parasites, and viruses. The mosquito defends itself by employing both physical …
Interaction of the tick immune system with transmitted pathogens
O Hajdušek, R Šíma, N Ayllón, M Jalovecká… - Frontiers in cellular …, 2013 - frontiersin.org
Ticks are hematophagous arachnids transmitting a wide variety of pathogens including
viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to …
viruses, bacteria, and protozoans to their vertebrate hosts. The tick vector competence has to …
The Plasmodium bottleneck: malaria parasite losses in the mosquito vector
Nearly one million people are killed every year by the malaria parasite Plasmodium.
Although the disease-causing forms of the parasite exist only in the human blood …
Although the disease-causing forms of the parasite exist only in the human blood …
Mosquito trilogy: microbiota, immunity and pathogens, and their implications for the control of disease transmission
In mosquitoes, the interaction between the gut microbiota, the immune system, and the
pathogens that these insects transmit to humans and animals is regarded as a key …
pathogens that these insects transmit to humans and animals is regarded as a key …
A Gut Symbiotic Bacterium Serratia marcescens Renders Mosquito Resistance to Plasmodium Infection Through Activation of Mosquito Immune Responses
L Bai, L Wang, J Vega-Rodríguez, G Wang… - Frontiers in …, 2019 - frontiersin.org
The malaria development in the mosquito midgut is a complex process that results in
considerable parasite losses. The mosquito gut microbiota influences the outcome of …
considerable parasite losses. The mosquito gut microbiota influences the outcome of …
Mosquito cellular immunity at single-cell resolution
Hemocytes limit the capacity of mosquitoes to transmit human pathogens. Here we profile
the transcriptomes of 8506 hemocytes of Anopheles gambiae and Aedes aegypti mosquito …
the transcriptomes of 8506 hemocytes of Anopheles gambiae and Aedes aegypti mosquito …