Imaging extracellular vesicles: current and emerging methods
STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
Technetium and gallium derived radiopharmaceuticals: comparing and contrasting the chemistry of two important radiometals for the molecular imaging era
MD Bartholoma, AS Louie, JF Valliant… - Chemical …, 2010 - ACS Publications
The objective of medical imaging using molecular probes and perfusion radiotracers is to
provide rapid, noninvasive evaluation of physiology, pathology, and/or organ function. The …
provide rapid, noninvasive evaluation of physiology, pathology, and/or organ function. The …
Current use and future potential of organometallic radiopharmaceuticals
R Schibli, AP Schubiger - European journal of nuclear medicine and …, 2002 - Springer
Contrary to common belief, organometallic compounds exhibit remarkable stability in
aerobic and even diluted aqueous solutions. Technetium-sestamibi (Cardiolite) is one of the …
aerobic and even diluted aqueous solutions. Technetium-sestamibi (Cardiolite) is one of the …
“Click to chelate”: synthesis and installation of metal chelates into biomolecules in a single step
TL Mindt, H Struthers, L Brans, T Anguelov… - Journal of the …, 2006 - ACS Publications
Click chemistry has been employed for the assembly of novel and efficient triazole-based
multidentate chelating systems while simultaneously attaching them to molecules of …
multidentate chelating systems while simultaneously attaching them to molecules of …
Influence of the Denticity of Ligand Systems on the in Vitro and in Vivo Behavior of 99mTc(I)−Tricarbonyl Complexes: A Hint for the Future Functionalization of …
Functionalization of biologically relevant molecules for the labeling with the novel fac-
[99mTc (OH2) 3 (CO) 3]+ precursor has gained considerable attention recently. Therefore …
[99mTc (OH2) 3 (CO) 3]+ precursor has gained considerable attention recently. Therefore …
Recent progress in fluorine-18 labelled peptide radiopharmaceuticals
S Okarvi - European journal of nuclear medicine, 2001 - Springer
The application of biologically active peptides labelled with positron-emitting nuclides has
emerged as a useful and interesting field in nuclear medicine. Small synthetic receptor …
emerged as a useful and interesting field in nuclear medicine. Small synthetic receptor …
Radiolabeling of Extracellular Vesicles with 99mTc for Quantitative In Vivo Imaging Studies
The biodistribution of extracellular vesicles (EVs) is a fundamental question in the field of
circulating biomarkers, which has recently gained attention. Despite the capabilities of …
circulating biomarkers, which has recently gained attention. Despite the capabilities of …
Fluorescent, phosphorescent, magnetic resonance contrast and radioactive tracer labelling of extracellular vesicles
This review focusses on the significance of fluorescent, phosphorescent labelling and
tracking of extracellular vesicles (EVs) for unravelling their biology, pathophysiology, and …
tracking of extracellular vesicles (EVs) for unravelling their biology, pathophysiology, and …
High‐resolution SPECT imaging of stimuli‐responsive soft microrobots
Untethered small‐scale robots have great potential for biomedical applications. However,
critical barriers to effective translation of these miniaturized machines into clinical practice …
critical barriers to effective translation of these miniaturized machines into clinical practice …
New directions in the coordination chemistry of 99mTc: a reflection on technetium core structures and a strategy for new chelate design
SR Banerjee, KP Maresca, L Francesconi… - Nuclear medicine and …, 2005 - Elsevier
Bifunctional chelates offer a general approach for the linking of radioactive metal cations to
macromolecules. In the specific case of 99mTc, a variety of technologies have been …
macromolecules. In the specific case of 99mTc, a variety of technologies have been …