Although better insights into the natural course of cystic fibrosis (CF) have led to treatment
approaches that have improved pulmonary health and increased the life expectancy of …

A biofilm is a structured consortium of bacteria embedded in a self-produced polymer matrix
consisting of polysaccharide, protein and DNA. Bacterial biofilms cause chronic infections …

Bacteria survive in nature by forming biofilms on surfaces and probably most, if not all,
bacteria (and fungi) are capable of forming biofilms. A biofilm is a structured consortium of …

In patients with cystic fibrosis (CF) lung damage secondary to chronic infection is the main
cause of death. Treatment of lung disease to reduce the impact of infection, inflammation …

Cost-of-illness studies, the systematic quantification of the economic burden of diseases on
the individual and on society, help illustrate direct budgetary consequences of diseases in …

Pseudomonas aeruginosa is a major cause of nosocomial infections. This organism shows
a remarkable capacity to resist antibiotics, either intrinsically (because of constitutive …

Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance
regulator (CFTR) gene [1, 2]. This results in dysfunction of the apical membrane CFTR …

In patients with cystic fibrosis (CF), early intervention and prevention of lung disease is of
paramount importance. Principles to achieve this aim include early diagnosis of CF, regular …

Chronic Pseudomonas aeruginosa lung infection in cystic fibrosis (CF) patients is caused by
biofilm-growing mucoid strains. Biofilms can be prevented by early aggressive antibiotic …

Chronic pulmonary infection with Pseudomonas aeruginosa is responsible for most of the
morbidity and mortality in cystic fibrosis (CF). Once established as a biofilm, chronic P …