Rett syndrome (RTT) is a neurological disorder caused by mutations in the X-linked gene
methyl-CpG-binding protein 2 (MECP2), a ubiquitously expressed transcriptional regulator …

Zebrafish are increasingly being utilized as a model system to investigate the function of the
growing list of risk genes associated with neurodevelopmental disorders. This is due in large …

Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are two
debilitating neurodevelopmental disorders. The former is associated with social impairments …

Autism spectrum disorders (ASDs) are a highly variable and complex set of neurological
disorders that alter neurodevelopment and cognitive function, which usually presents with …

Central nervous system injury re-initiates neurogenesis in anamniotes (amphibians and
fishes), but not in mammals. Activation of the innate immune system promotes regenerative …

Adolescent idiopathic scoliosis (AIS) affects 3% to 4% of children between the ages of 11
and 18 [1, 2]. This disorder, characterized by abnormal three-dimensional spinal curvatures …

Autism spectrum disorders (ASD) affect about 1% of the population and are strongly
associated with gastrointestinal diseases creating shortcomings in quality of life. Multiple …

Tumor necrosis factors (TNFs) are a group of cytokines that play critical roles in regulating a
diverse range of physiological processes in vertebrates. TNFs function by activating a large …

Autism Spectrum Disorders (ASD) affect around 1.5% of the global population, which
manifest alterations in communication and socialization, as well as repetitive behaviors or …

Neuroinflammation is a cause of neurodevelopmental disorders such as autism spectrum
disorders, fetal alcohol syndrome, and cerebral palsy. Converging lines of evidence from …