The semantics of microglia activation: neuroinflammation, homeostasis, and stress

SC Woodburn, JL Bollinger, ES Wohleb - Journal of neuroinflammation, 2021 - Springer
Microglia are emerging as critical regulators of neuronal function and behavior in nearly
every area of neuroscience. Initial reports focused on classical immune functions of …

[HTML][HTML] Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - Elsevier
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Post-COVID-19 depressive symptoms: epidemiology, pathophysiology, and pharmacological treatment

MG Mazza, M Palladini, S Poletti, F Benedetti - CNS drugs, 2022 - Springer
Abstract The Coronavirus Disease 2019 (COVID-19) pandemic is still spreading worldwide
over 2 years since its outbreak. The psychopathological implications in COVID-19 survivors …

Negative feedback control of neuronal activity by microglia

A Badimon, HJ Strasburger, P Ayata, X Chen, A Nair… - Nature, 2020 - nature.com
Microglia, the brain's resident macrophages, help to regulate brain function by removing
dying neurons, pruning non-functional synapses, and producing ligands that support …

Psychiatric and neuropsychiatric presentations associated with severe coronavirus infections: a systematic review and meta-analysis with comparison to the COVID …

JP Rogers, E Chesney, D Oliver, TA Pollak… - The Lancet …, 2020 - thelancet.com
Background Before the COVID-19 pandemic, coronaviruses caused two noteworthy
outbreaks: severe acute respiratory syndrome (SARS), starting in 2002, and Middle East …

[HTML][HTML] Mitochondrial impairment: A common motif in neuropsychiatric presentation? The link to the tryptophan–kynurenine metabolic system

M Tanaka, Á Szabó, E Spekker, H Polyák, F Tóth… - Cells, 2022 - mdpi.com
Nearly half a century has passed since the discovery of cytoplasmic inheritance of human
chloramphenicol resistance. The inheritance was then revealed to take place maternally by …

The conundrum of 'long-COVID-19: a narrative review

M Garg, M Maralakunte, S Garg, S Dhooria… - … journal of general …, 2021 - Taylor & Francis
COVID-19 is an ongoing pandemic with many challenges that are now extending to its
intriguing long-term sequel.'Long-COVID-19ʹ is a term given to the lingering or protracted …

Early-life inflammation promotes depressive symptoms in adolescence via microglial engulfment of dendritic spines

P Cao, C Chen, A Liu, Q Shan, X Zhu, C Jia, X Peng… - Neuron, 2021 - cell.com
Early-life inflammation increases the risk for depression in later life. Here, we demonstrate
how early-life inflammation causes adolescent depressive-like symptoms: by altering the …

Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model

RB Price, R Duman - Molecular psychiatry, 2020 - nature.com
Chronic stress and depressive-like behaviors in basic neuroscience research have been
associated with impairments of neuroplasticity, such as neuronal atrophy and synaptic loss …

Depression and its phytopharmacotherapy—a narrative review

L Dobrek, K Głowacka - International Journal of Molecular Sciences, 2023 - mdpi.com
Depression is a mental health disorder that develops as a result of complex psycho-neuro-
immuno-endocrinological disturbances. This disease presents with mood disturbances …