Facing the explosive growth of biological sequence data, such as those of protein/peptide
and DNA/RNA, generated in the post-genomic age, many bioinformatical and mathematical …

The eternal or ultimate goal of medicinal chemistry is to find most effective ways to treat
various diseases and extend human beings' life as long as possible. Human being is a …

Wenxiang diagram is a new two-dimensional representation that characterizes the
disposition of hydrophobic and hydrophilic residues in α-helices. In this research, the …

The growing incidences of new viral diseases and increasingly frequent viral epidemics
have strained therapeutic and preventive measures; the high mutability of viral genes puts …

Colorectal cancer is one of the most frequent types of cancer in the world and generates
important social impact. The understanding of the specific metabolism of this disease and …

There is a need for the study of complex diseases due to their important impact on our
society. One of the solutions involves the theoretical methods which are fast and efficient …

A new method of comparison of protein sequences has been formulated. The sequence of
amino acids is represented by a set of point masses in a 20D space. The distribution of …

Background Rotaviral diarrhoea kills about half a million children annually in develo**
countries and accounts for one third of diarrhea related hospitalizations. Drugs and vaccines …

In this work, we study the global dynamics of a new SIRI epidemic model with
demographics, graded cure and relapse in a complex heterogeneous network. First, we …

In this article, we introduce three 3D graphical representations of DNA primary sequences,
which we call RY-curve, MK-curve and SW-curve, based on three classifications of the DNA …