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Genome-wide analysis identifies novel loci influencing plasma apolipoprotein E concentration and Alzheimer's disease risk
Abstract The APOE 2/3/4 polymorphism is the greatest genetic risk factor for Alzheimer's
disease (AD). This polymorphism is also associated with variation in plasma ApoE level; …
disease (AD). This polymorphism is also associated with variation in plasma ApoE level; …
Fatty liver disease in children (MAFLD/PeFLD Type 2): unique classification considerations and challenges
R Hegarty, E Kyrana, E Fitzpatrick… - … in Endocrinology and …, 2023 - journals.sagepub.com
In children, fatty liver disease is a group of disorders that often overlaps with inherited
metabolic disorders (IMDs), which requires prompt diagnosis and specific management …
metabolic disorders (IMDs), which requires prompt diagnosis and specific management …
Genetic associations vary across the spectrum of fasting serum insulin: results from the European IDEFICS/I. Family children's cohort
Aims/hypothesis There is increasing evidence for the existence of shared genetic predictors
of metabolic traits and neurodegenerative disease. We previously observed a U-shaped …
of metabolic traits and neurodegenerative disease. We previously observed a U-shaped …