Sex differences in endothelial function important to vascular health and overall cardiovascular disease risk across the lifespan
Diseases of the cardiovascular system are the leading cause of morbidity and mortality in
men and women in developed countries, and cardiovascular disease (CVD) is becoming …
men and women in developed countries, and cardiovascular disease (CVD) is becoming …
Sex differences in cardiovascular actions of the renin–angiotensin system
D Medina, D Mehay, AC Arnold - Clinical Autonomic Research, 2020 - Springer
Cardiovascular disease (CVD) remains a worldwide public health concern despite decades
of research and the availability of numerous targeted therapies. While the intrinsic …
of research and the availability of numerous targeted therapies. While the intrinsic …
Androgens in maternal vascular and placental function: implications for preeclampsia pathogenesis
Adequate maternal vascular adaptations and blood supply to the uterus and placenta are
crucial for optimal oxygen and nutrient transport to growing fetuses of eutherian mammals …
crucial for optimal oxygen and nutrient transport to growing fetuses of eutherian mammals …
Sex differences in the metabolic effects of the renin-angiotensin system
Obesity is a global epidemic that greatly increases risk for develo** cardiovascular
disease and type II diabetes. Sex differences in the obese phenotype are well established in …
disease and type II diabetes. Sex differences in the obese phenotype are well established in …
Reactive oxygen species: players in the cardiovascular effects of testosterone
Androgens are essential for the development and maintenance of male reproductive tissues
and sexual function and for overall health and well being. Testosterone, the predominant …
and sexual function and for overall health and well being. Testosterone, the predominant …
Elevated testosterone reduces uterine blood flow, spiral artery elongation, and placental oxygenation in pregnant rats
Elevated maternal testosterone levels are shown to cause fetal growth restriction, eventually
culminating in sex-specific adult-onset hypertension that is more pronounced in males than …
culminating in sex-specific adult-onset hypertension that is more pronounced in males than …
Testosterone plays a permissive role in angiotensin II-induced hypertension and cardiac hypertrophy in male rats
Sex hormones contribute to sex differences in blood pressure. Inappropriate activation of the
renin-angiotensin system is involved in vascular dysfunction and hypertension. This study …
renin-angiotensin system is involved in vascular dysfunction and hypertension. This study …
Reduced AT2R Signaling Contributes to Endothelial Dysfunction After Preeclampsia
KS Schwartz, M Sun, DI Jalal, MK Santillan… - …, 2024 - ahajournals.org
BACKGROUND: Women who had preeclampsia (a history of preeclampsia) have a> 4-fold
risk of develo** cardiovascular disease compared with women who had an …
risk of develo** cardiovascular disease compared with women who had an …
Polycystic ovary syndrome as a paradigm for prehypertension, prediabetes, and preobesity
The polycystic ovary syndrome (PCOS) is a hyperandrogenic disorder affecting 5–10% of
premenopausal women. These patients gather multiple cardiovascular risk factors from early …
premenopausal women. These patients gather multiple cardiovascular risk factors from early …
Pre-transplant screening for non-HLA antibodies: who should be tested?
Retrospective studies of angiotensin II type 1 receptor antibodies (AT1R-Ab) and anti-
endothelial cell antibodies (AECA) have linked these antibodies to allograft injury. Because …
endothelial cell antibodies (AECA) have linked these antibodies to allograft injury. Because …