In this narrative review, a theoretical framework on the crosstalk between physical exercise
and blood-brain barrier (BBB) permeability is presented. We discuss the influence of …

The present paper reviews astrocyte pathology in major depressive disorder (MDD) and
proposes that reductions in astrocytes and related markers are key features in the pathology …

This article introduces the special issue on “Blood–Brain Barrier and Epilepsy.” We review
briefly current understanding of the structure and function of the blood–brain barrier (BBB) …

BACKGROUND: Depression and cerebrovascular disease influence each other, according
to clinical studies. Despite this evidence, no studies have investigated the relationship …

The protection of the brain from blood‐borne toxins, proteins, and cells is critical to the
brain's normal function. Accordingly, a compromise in the blood–brain barrier (BBB) function …

The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was
published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater …

The ACh hydrolyzing enzyme acetylcholinesterase (AChE) is a combinatorial series of
proteins with variant N and C termini generated from alternate promoter usage and 3 …

In Alzheimer's disease, both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)
colocalize with brain fibrils of amyloid-β (Aβ) peptides, and synaptic AChE-S facilitates fibril …

The entorhinal cortex–hippocampus complex is believed to be the site of origin of seizure
activity in the majority of patients with temporal lobe epilepsy (TLE). Both these regions are …

Rett syndrome (RTT, online MIM 312750) is a devastating neurodevelopmental disorder
characterized by motor and cognitive disabilities. It is mainly caused by pathogenetic …