Advancements in in silico techniques of lead molecule selection have resulted in the failure
of around 70% of new chemical entities (NCEs). Some of these molecules are getting …

Nanocrystals are pure drug crystals with sizes in the nanometer range. Due to the
advantages of high drug loading, platform stability, and ease of scaling-up, nanocrystals …

Conventional cancer chemotherapy heavily relies on the use of cytotoxic agents, which
typically do not preferentially localize at the tumor site and cause toxicity to normal organs …

Poor solubility of drug compounds is a great issue in drug industry today and decreasing
particle size is one efficient and simple way to overcome this challenge. Drug nanocrystals …

Although a number of techniques exist for generating structured organic nanocomposites, it
is still challenging to fabricate them in a controllable, yet universal and scalable manner. In …

Nanocrystals show promise to deliver poorly water-soluble drugs to yield systemic exposure.
However, our knowledge regarding the in vivo fate of nanocrystals is in its infancy, as …

The discipline of neurotheranostics was forged to improve diagnostic and therapeutic
clinical outcomes for neurological disorders. Research was facilitated, in largest measure …

The controlled synthesis of functional nanoparticles with tunable structures and properties
has been extensively investigated for cancer treatment and diagnosis. Among a variety of …

Highlights•Nanocrystals are unique delivery systems with drug loading up to
100%.•Nanocrystals made from a definite drug differ in their performance.•Experience …

Low level laser therapy (LLLT) is known as a safe type of phototherapy to target tumor
tissue/cells. Besides, using targeted nanoparticles increases the successfulness of cancer …