Coenzyme Q10 in cardiovascular and metabolic diseases: current state of the problem

VI Zozina, S Covantev, OA Goroshko… - Current cardiology …, 2018 - ingentaconnect.com
The burden of cardiovascular and metabolic diseases is increasing with every year.
Although the management of these conditions has improved greatly over the years, it is still …

[HTML][HTML] Coenzyme Q10: Clinical applications in cardiovascular diseases

A Martelli, L Testai, A Colletti, AFG Cicero - Antioxidants, 2020 - mdpi.com
Coenzyme Q 10 (CoQ 10) is a ubiquitous factor present in cell membranes and
mitochondria, both in its reduced (ubiquinol) and oxidized (ubiquinone) forms. Its levels are …

[HTML][HTML] The nicotinamide/streptozotocin rodent model of type 2 diabetes: renal pathophysiology and redox imbalance features

LJ Yan - Biomolecules, 2022 - mdpi.com
Diabetic nephropathy (DN) is a common complication of diabetes mellitus. While there has
been a great advance in our understanding of the pathogenesis of DN, no effective …

Modulating impacts of quercetin/sitagliptin combination on streptozotocin-induced diabetes mellitus in rats

HE Eitah, YA Maklad, NF Abdelkader… - Toxicology and applied …, 2019 - Elsevier
Background Since many diabetic patients require combination therapy, the use of herbal
remedies with anti-diabetic activity represents a vital option in diabetes mellitus (DM) …

Dietary modulation of oxidative stress in Alzheimer's disease

A Thapa, NJ Carroll - International journal of molecular sciences, 2017 - mdpi.com
Cells generate unpaired electrons, typically via oxygen-or nitrogen-based by-products
during normal cellular respiration and under stressed situations. These pro-oxidant …

Coenzyme Q10 prevents oxidative stress and fibrosis in isoprenaline induced cardiac remodeling in aged rats

A Ulla, MK Mohamed, B Sikder, AFMT Rahman… - BMC Pharmacology and …, 2017 - Springer
Background The objective of the present study aimed to investigate the effect of CoQ10
treatment on isoprenaline (ISO)-induced cardiac remodeling in rats. Methods Rats were …

Maackiain protects the kidneys of type 2 diabetic rats via modulating the Nrf2/HO-1 and TLR4/NF-κB/Caspase-3 pathways

J Guo, J Li, H Wei, Z Liang - Drug Design, Development and …, 2021 - Taylor & Francis
Background Type 2 diabetes (T2D) is aglobal health burden that accounts for about 90% of
all cases of diabetes. Injury to the kidneys is aserious complication of type 2 diabetes …

A comparative study of the role of crocin and sitagliptin in attenuation of STZ-induced diabetes mellitus and the associated inflammatory and apoptotic changes in …

MM Samaha, E Said, HA Salem - Environmental Toxicology and …, 2019 - Elsevier
Type 1 diabetes mellitus (T1DM) describes a complex group of metabolic disorders
associated with elevated blood glucose levels and increased risks of complications …

Impact of dyslipidemia in the development of cardiovascular complications: delineating the potential therapeutic role of coenzyme Q10

SXH Mthembu, P Orlando, S Silvestri, K Ziqubu… - Biochimie, 2023 - Elsevier
Dyslipidemia is one of the major risk factors for the development of cardiovascular disease
(CVD) in patients with type 2 diabetes (T2D). This metabolic anomality is implicated in the …

Combination of coenzyme Q10-loaded liposomes with ultrasound targeted microbubbles destruction (UTMD) for early theranostics of diabetic nephropathy

T Yue, HL Xu, PP Chen, L Zheng, Q Huang… - International Journal of …, 2017 - Elsevier
Diabetic nephropathy (DN) is one of the most common and lethal microvascular
complications of diabetes. This study aimed to explore whether coenzymeQ10 (CoQ10) as …