Efficacy of vitamin D3 supplementation on cancer mortality: Systematic review and individual patient data meta-analysis of randomised controlled trials

S Kuznia, A Zhu, T Akutsu, JE Buring… - Ageing research …, 2023 - Elsevier
To evaluate the effect of vitamin D 3 supplementation on cancer mortality in the general
population and on prognosis in cancer patients, a systematic review and meta-analysis of …

Infections and autoimmunity—the Immune System and vitamin D: a systematic review

SJ Wimalawansa - Nutrients, 2023 - mdpi.com
Both 25-autoimmunity and (25 (OH) D: calcifediol) and its active form, 1, 25-dihydroxyvitamin
D (1, 25 (OH) 2D: calcitriol), play critical roles in protecting humans from invasive pathogens …

Effect of vitamin D supplements on relapse or death in a p53-immunoreactive subgroup with digestive tract cancer: post hoc analysis of the AMATERASU randomized …

K Kanno, T Akutsu, H Ohdaira, Y Suzuki… - JAMA Network …, 2023 - jamanetwork.com
Importance Recent meta-analyses of randomized clinical trials found that daily vitamin D3
supplementation had beneficial effects on cancer mortality, although the results are still …

Vitamin D in cancer prevention: gaps in current knowledge and room for hope

M Henn, V Martin-Gorgojo, JM Martin-Moreno - Nutrients, 2022 - mdpi.com
Intensive epigenome and transcriptome analyses have unveiled numerous biological
mechanisms, including the regulation of cell differentiation, proliferation, and induced …

The preventive role of the vitamin D endocrine system in cervical cancer

E Avila, BJ Noriega-Mejía, J González-Macías… - International Journal of …, 2023 - mdpi.com
Vitamin D along with its active metabolite calcitriol and its metabolic and signaling system,
known as the vitamin D endocrine system, have been widely recognized as a pivotal …

Vitamin D intake, serum 25-hydroxyvitamin-D (25 (OH) D) levels, and cancer risk: a comprehensive meta-meta-analysis including meta-analyses of randomized …

ME Arayici, Y Basbinar, H Ellidokuz - Nutrients, 2023 - mdpi.com
It is a well-established fact that inadequate Vitamin D (Vit-D) levels have negative effects on
the development and progression of malignant diseases, particularly cancer. The purpose of …

[HTML][HTML] Vitamin D in cancer prevention and treatment: A review of epidemiological, preclinical, and cellular studies

S Dallavalasa, SRV Tulimilli, VG Bettada, M Karnik… - …, 2024 - pmc.ncbi.nlm.nih.gov
Simple Summary Inhibition of human cancers has previously been linked to the
administration of vitamin D. Studies have shown that increased cancer incidence is …

Exploiting vitamin D receptor and its ligands to target squamous cell carcinomas of the head and neck

L Koll, D Gül, MI Elnouaem, H Raslan… - International journal of …, 2023 - mdpi.com
Vitamin D (VitD) and its receptor (VDR) have been intensively investigated in many cancers.
As knowledge for head and neck cancer (HNC) is limited, we investigated the (pre) clinical …

Engineering heterogeneous tumor models for biomedical applications

Z Wu, D Huang, J Wang, Y Zhao, W Sun… - Advanced …, 2024 - Wiley Online Library
Tumor tissue engineering holds great promise for replicating the physiological and
behavioral characteristics of tumors in vitro. Advances in this field have led to new …

Scientific opinion on the tolerable upper intake level for vitamin D, including the derivation of a conversion factor for calcidiol monohydrate

EFSA Panel on Nutrition, Novel Foods and … - EFSA …, 2023 - Wiley Online Library
Following two requests from the European Commission (EC), the EFSA Panel on Nutrition,
Novel Foods and Food Allergens (NDA) was asked to deliver a scientific opinion on the …