[HTML][HTML] Potential therapeutic natural products against Alzheimer's disease with Reference of Acetylcholinesterase

S Ahmed, ST Khan, MK Zargaham, AU Khan… - Biomedicine & …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), is the most common type of dementia primarily affecting
the later years of life. Its prevalence is likely to increase in any aging population and will be a …

Antibacterial activities of the extracts, fractions and isolated compounds from Canarium patentinervium Miq. against bacterial clinical isolates

R Mogana, A Adhikari, MN Tzar, R Ramliza… - … medicine and therapies, 2020 - Springer
Background Canarium patentinervium leaves are used by the local indigenous people of
Malaysia for wound healing. The current study is undertaken to screen the comprehensive …

Flavonoids as promising multitarget agents in Alzheimer's Disease Therapy

E Lima, AP Rauter, J Medeiros - Applied Sciences, 2023 - mdpi.com
The increase in the occurrence of the multifactorial Alzheimer's disease (AD) demands an
urgent effort towards the development of effective anti-AD agents, such as the multitarget …

Chemical and bioinformatics analyses of the anti-leishmanial and anti-oxidant activities of hemp essential oil

L Menghini, C Ferrante, S Carradori, M D'Antonio… - Biomolecules, 2021 - mdpi.com
Industrial hemp is a multiuse crop that has been widely cultivated to produce fibers and
nutrients. The capability of the essential oil (EO) from inflorescences as antimicrobial agent …

Rhodauricanol A, an analgesic diterpenoid with an unprecedented 5/6/5/7 tetracyclic system featuring a unique 16-oxa-tetracyclo [11.2. 1.01, 5.07, 13] hexadecane …

Y Feng, S Zha, H Zhang, B Gao, G Zheng, P **… - Chinese Chemical …, 2023 - Elsevier
A novel diterpenoid with an unprecedented 5/6/5/7 tetracyclic system, rhodauricanol A (1),
five new grayanane-derived diterpenoids, dauricanols A− E (2− 6), and five known ones (7 …

[HTML][HTML] Antiplasmodial and Antileishmanial Activities of a New Limonoid and Other Constituents from the Stem Bark of Khaya senegalensis

GA Amang à Ngnoung, YO Nganso Ditchou… - Molecules, 2023 - mdpi.com
Plasmodium falciparum and Leishmania sp. resistance to antiparasitic drugs has become a
major concern in malaria and leishmaniasis control. These diseases are public health …

Biological activity of coumarin derivatives as anti-leishmanial agents

V Mandlik, S Patil, R Bopanna, S Basu, S Singh - PLoS One, 2016 - journals.plos.org
Cutaneous leishmaniasis affects nearly 0.7 to 1.3 million people annually. Treatment of this
disease is difficult due to lack of appropriate medication and the growing problem of drug …

Design, synthesis, and repurposing of O6-aminoalkyl-sulfuretin analogs towards discovery of potential lead compounds as antileishmanial agents

AHE Hassan, TN Phan, S Moon, CH Lee, YJ Kim… - European Journal of …, 2023 - Elsevier
Up to date, there are still significantly unmet clinical needs for treatment of the fatal visceral
leishmaniasis; a neglected tropical disease. Herein, a recently reported antileishmanial hit …

In vitro cholinesterase inhibitory action of Cannabis sativa L. Cannabaceae and in silico study of its selected phytocompounds

I Karimi, N Yousofvand, BA Hussein - In Silico Pharmacology, 2021 - Springer
Cannabis sativa L. Cannabaceae, used for psychoactive rituals in Mesopotamia. Here, we
investigated in vitro inhibitory activity of methyl alcohol extract derived from leaves and resin …

[HTML][HTML] An integrative analysis to predict the active compounds and explore polypharmacological mechanisms of Orthosiphon stamineus Benth.

X Wang, W Zhao, X Zhang, Z Wang, C Han, J Xu… - Computers in Biology …, 2023 - Elsevier
Abstract Background Orthosiphon stamineus Benth is a dietary supplement and traditional
Chinese herb with widespread clinical applications, but a comprehensive understanding of …